Behçet’s disease (BD) is a systemic vasculitis characterised by a relapsing remitting course, affecting multiple organ systems. BD can present numerous signs and symptoms that, initially, do not seem to be related. These symptoms include recurrent oral aphthous and genital ulcers, uveitis and skin lesions. The effects of BD vary by person and can, in some cases, heal themselves.
In the eye, BD is a cause of potentially blinding inflammation in the form of uveitis. Uveitis causes blurred vision, redness, pain and worse visual outcome in one or both eyes. Ocular BD affects between 50% and 90% of BD sufferers depending on the geographic location: can be found most commonly in the Middle East and Far East, particularly Japan.
Treatment consists of medications to reduce the signs and symptoms of BD and prevent serious complications, such as blindness.