Scientific corner

Efficacy of apheresis as maintenance therapy for patients with ulcerative colitis in an open-label prospective multicenter randomised controlled trial

Makoto NaganumaYoko YokoyamaSatoshi MotoyaKenji WatanabeKoji SawadaFumito HiraiTakayuki YamamotoHiroyuki HanaiTeppei OmoriTakanori Kanai & Toshifumi Hibi, Journal of Gastroenterology volume 55, pages390–400 (2020)

Apheresis was well tolerated as maintenance therapy for UC although the cumulative clinical remission rate at 12 months was comparable between the apheresis and control groups.

Efficacy of apheresis as maintenance therapy for patients with ulcerative colitis in an open-label prospective multicenter https://link.springer.com/article/10.1007/s00535-019-01651-0#group-1

Scientific corner

A randomised, double-blind, sham-controlled study of granulocyte/monocyte apheresis for moderate to severe Crohn’s disease.

Bruce E Sands 1Seymour KatzDouglas C WolfBrian G FeaganTao WangLisa-Marie GustofsonCindy WongMargaret K VandervoortStephen Hanauer, Gut. 2013 Sep;62(9):1288-94.

GMA was well tolerated, but this study did not demonstrate its effectiveness over a sham procedure in inducing clinical remission or response in patients with moderate to severe CD.

https://pubmed.ncbi.nlm.nih.gov/22760005/

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