Scientific corner

Targeting of CD163+ Macrophages in Inflammatory and Malignant Diseases

Maria K. Skytthe,1 Jonas Heilskov Graversen,1,* and Søren K. Moestrup, Int J Mol Sci. 2020 Aug; 21(15): 5497.

In conclusion, the specific targeting of CD163+ macrophages has been demonstrated to be a promising drug delivery strategy for handling inflammatory and malignant disease, contributing to the current pharmaceutical therapies.


Scientific corner

Sequential therapy consisting of glucocorticoid infusions followed by granulocyte-monocyte absorptive apheresis in patients with severe alcoholic hepatitis.

Kazuhiro Watanabe 1Yoshihito Uchida 1Kayoko Sugawara 1Kayoko Naiki 1Mie Inao 1Nobuaki Nakayama 1Satoshi Mochida 2 , J Gastroenterol 2017 Jul;52(7):830-837.

Sequential therapy combining glucocorticoid infusion and GMA was useful for attenuating liver injuries in patients with severe alcoholic hepatitis by preventing rebound increases in inflammatory reactions after discontinuation of glucocorticoid infusions, except in patients with bacterial infections and/or multiple organ failure.

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