Scientific corner

Successful treatment of recurrent subcutaneous abscesses using granulocyte and monocyte adsorptive apheresis

Ken Okamura 1, Mariko Nikaido 1, Toru Saito 1, Yosuke Arai 1, Chiharu Yoshioka 1, Makoto Yagi 2, Hitomi Komoriya 3, Nana Takahashi 3, Yutaka Hozumi 1, Tamio Suzuki J Dermatol . 2024 Mar 20. doi: 10.1111/1346-8138.17198.

Scientific corner

Rapidly Progressing Aseptic Abscesses in a Patient with Ulcerative Colitis

Yoshiharu Yamaguchi 1Marie Nakagawa 1Shoko Nakagawa 1Kazuhiro Nagao 1Satoshi Inoue 1Tomoya Sugiyama 1Shinya Izawa 1Yasutaka Hijikata 1Masahide Ebi 1Yasushi Funaki 1Naotaka Ogasawara 1Makoto Sasaki 1Kunio Kasugai 1 Intern Med  2021 Mar 1;60(5):725-730. doi: 10.2169/internalmedicine.5733-20. Epub 2020 Sep 30.

Aseptic abscesses (AAs) are extraintestinal manifestations of inflammatory bowel disease (IBD). IBD-associated AAs are rare in Japan. We treated a 45-year-old man with ulcerative colitis (UC)-associated AAs. During remission, multiple progressive abscesses were detected in the spleen; he underwent splenectomy because an infectious disease was suspected. Although his condition improved temporarily after splenectomy, a large liver abscess was noted, and a diagnosis of UC-associated AAs was made. Granulocytapheresis (GCAP) and infliximab (IFX) administration resolved the abscess. This is the first reported case of UC-associated AAs in a Japanese patient treated by splenectomy, GCAP, and IFX.

https://pubmed.ncbi.nlm.nih.gov/32999240/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990631/

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