Ken Okamura 1, Mariko Nikaido 1, Toru Saito 1, Yosuke Arai 1, Chiharu Yoshioka 1, Makoto Yagi 2, Hitomi Komoriya 3, Nana Takahashi 3, Yutaka Hozumi 1, Tamio Suzuki J Dermatol . 2024 Mar 20. doi: 10.1111/1346-8138.17198.

Yoshiharu Yamaguchi ¹, Marie Nakagawa ¹, Shoko Nakagawa ¹, Kazuhiro Nagao ¹, Satoshi Inoue ¹, Tomoya Sugiyama ¹, Shinya Izawa ¹, Yasutaka Hijikata ¹, Masahide Ebi ¹, Yasushi Funaki ¹, Naotaka Ogasawara ¹, Makoto Sasaki ¹, Kunio Kasugai ¹ Intern Med  2021 Mar 1;60(5):725-730. doi: 10.2169/internalmedicine.5733-20. Epub 2020 Sep 30.

Aseptic abscesses (AAs) are extraintestinal manifestations of inflammatory bowel disease (IBD). IBD-associated AAs are rare in Japan. We treated a 45-year-old man with ulcerative colitis (UC)-associated AAs. During remission, multiple progressive abscesses were detected in the spleen; he underwent splenectomy because an infectious disease was suspected. Although his condition improved temporarily after splenectomy, a large liver abscess was noted, and a diagnosis of UC-associated AAs was made. Granulocytapheresis (GCAP) and infliximab (IFX) administration resolved the abscess. This is the first reported case of UC-associated AAs in a Japanese patient treated by splenectomy, GCAP, and IFX.

https://pubmed.ncbi.nlm.nih.gov/32999240/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990631/