GMA Apheresis time

Calculation of GMA apheresis time based on patient weight:

1. Select gender: Male / Female

2. Select weight:


A minimum of 60 minutes of apheresis at 30 ml/min or processing at least 1800cc of blood is always recommended, although there are evidence supporting higher efficacy and no safety concern obtained by processing larger volumes of blood (90 or more min)1,2

Also the intensive regimen (2 sessions/week) showed higher rate of clinical remission and a significantly shorter time to remission (14.9 ± 9.5 vs 28.1 ± 16.9 days; P < 0.0001) significantly reducing the patients' morbidity time without increasing the incidence of side effects.3

In patients weighing >100kg, apheresis time should be assessed on an individual basis.

Useful link to calculate pediatric blood volume:

Pediatric Blood Volume Calculator (

Processed BV for apheresis in children should not be below 1.333ml to avoid hemorrhagic shock.

+10-15% margin so:
1.333ml +10%= 1.466 (>= 19,5kg) +200ml fuera=1.666 (>22,3 kg)
1.333ml +15%=1.533 (>=20,5kg) +200ml fuera=1.733 (>23,3 Kg)

A brief review of common mathematical calculations in therapeutic apheresis - Staley - 2019 - Journal of Clinical Apheresis - Wiley Online Library

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