Shuzo Kaneko 1, Tsuyoshi Zen 1, Susumu Banjoya 2, Toshiaki Nuki 3, Ainori Hoshimoto 1, Makiko Harano 1, Sou Hagiwara 1, Eri Imai 1, Yusuke Tsukamoto 1 Intern Med. 2023 Sep 1;62(17):2565-2569. doi: 10.2169/internalmedicine.1728-23.
Tag: pericarditis
Scientific corner
Successful Use of Granulocyte and Monocyte Adsorptive Apheresis in a Patient with Post-COVID-19 Multisystem Inflammatory Syndrome in Adults
Multisystem inflammatory syndrome in adults (MIS-A) is a life-threatening disease that can develop weeks after coronavirus disease 2019 (COVID-19). MIS-A symptoms include multiorgan involvement, especially gastrointestinal tract and heart involvement, and Kawasaki disease-like symptoms. We herein report a 44-year-old Japanese man with MIS-A who had contracted COVID-19 five weeks ago and went into shock after acute gastroenteritis, acute kidney injury, and Kawasaki disease-like symptoms. Methylprednisone pulse and high-dose intravenous immunoglobulin resulted in recovery of shock and his renal function, but diffuse ST-segment elevation on electrocardiography and pericardial effusion with a fever emerged after therapy. Additional granulocyte-monocyte adsorptive apheresis successfully ameliorated the cardiac involvement.
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