Scientific corner

Sweet’s Syndrome Successfully Treated with Granulocyte and Monocyte Adsorption Apheresis.

Asami Fujii 1Yoko Mizutani 1Yuki Hattori 1Tomoko Takahashi 1Hidenori Ohnishi 2Shozo Yoshida 3Mariko Seishima 1 , Case Rep Dermatol. 2017 May 22;9(2):13-18.

After the first session of GMA therapy, all symptoms including the erythematous lesions and fever were completely resolved, and serum G-CSF level was reduced. Leukocyte count, neutrophil count, serum amyloid A protein, and CRP levels were restored within normal ranges by 2 weeks. Thus, GMA therapy can successfully treat a patient with recurrent Sweet’s syndrome, potentially related to the restoration of elevated serum G-CSF levels.

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