Ken Fukunaga 1, Yoko Yokoyama, Koji Kamikozuru, Koji Yoshida, Risa Kikuyama, Kazuko Nagase, Shiro Nakamura, Yoshiyuki Takei, Hiroto Miwa, Takayuki Matsumoto, J Clin Apher. 2010;25(4):226-8.
Selective depletion of peripheral granulocyte/monocyte enhances the efficacy of scheduled maintenance infliximab in Crohn’s disease
IFX appears to induce and maintain remission of CD, but it may lose its efficacy after repeated administration. GMA is safe and by selectively depleting elevated/activated leukocytes may be a useful adjunct for IFX efficacy.
Clinical remission / combination / Infliximab / maintenance / Safety /
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