Granulocyte/monocyte adsorptive apheresis for the treatment of therapy-refractory chronic active　ulcerative colitis

Axel Dignass ¹, Ayesha Akbar ², Daniel C Baumgart ³, Gilles Bommelaer ⁴, Guillaume Bouguen ⁵, Guillaume Cadiot ⁶, Anton Gillessen ⁷, Jean-Charles Grimaud ⁸, Ailsa Hart ², Syed Hoque ⁹, Richard Makins ¹⁰, Christophe Michiels ¹¹, Jacques Moreau ¹², Purushothaman Premchand ¹³, Wolfgang Ramlow ¹⁴, Stefan Schanz ¹⁵, Sreedhar Subramanian ¹⁶, Christian von Tirpitz ¹⁷, Bruno Bonaz ¹⁸ , Scand J Gastroenterol. 2018 Apr;53(4):442-448.

This study confirms findings of the 12-week interim analysis and demonstrates that GMA apheresis provides a safe and beneficial long-term outcome for patients with chronic active UC resistant/intolerant to IS and/or TNF inhibitors.

https://pubmed.ncbi.nlm.nih.gov/29513111/