Tumor necrosis factor-α-secreting CD16+ antigen presenting cells are effectively removed by granulocytapheresis in ulcerative colitis patients

Joaquin Sanchez-Garcia ¹, Juana Serrano-López, Valle García-Sanchez, Miguel A Alvarez-Rivas, Rosario Jimenez-Moreno, Carlos Pérez-Seoane, Concepcion Herrera-Arroyo, Josefina Serrano, Juan F de Dios, Antonio Torres-Gomez, J Gastroenterol Hepatol. 2010 Dec;25(12):1869-75

The effect of GCAP in peripheral blood APC consisted mainly on a significant depletion of tumor necrosis factor-α secreting CD16-mDC. This finding could suggest a potential mechanism of GCAP beneficial effect that must be confirmed in larger series.

https://pubmed.ncbi.nlm.nih.gov/21091999/