Scientific corner

Therapeutic depletion of myeloid lineage leucocyte in patients with generalized pustular psorasis indicates a major role for neutrophiles in the immunopathogenesis of psoriasis

Shigaku Ikeda 1Hidetoshi Takahashi 2Yasushi Suga 3Hikaru Eto 4Takafumi Etoh 5Keiko Okuma 6Kazuo Takahashi 7Takeshi Kanbara 8Mariko Seishima 9Akimichi Morita 10Yasutomo Imai 11Takuro Kanekura 12 , J Am Acad Dermatol. 2013 Apr;68(4):609-617.

GMA in this clinical setting was safe and effective, suggested a major role for granulocytes/monocytes in the immunopathogenesis of GPP.

https://pubmed.ncbi.nlm.nih.gov/23332516/

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