Scientific corner

Selective white cell apheresis reduces relapse rates in patients with IBD at significant risk of clinical relapse

Laurence Maiden 1Ken TakeuchiRosie BaurIngi BjarnasonJohn O’DonohueIan ForgacsGuy Chung-FayeJeremy SandersonIngvar Bjarnason, Inflamm Bowel Dis. 2008 Oct;14(10):1413-8.

This study represents a new approach to the treatment of IBD by targeting a group of asymptomatic patients for treatment who are at significant risk of relapse based on high fecal calprotectin concentrations. Selective leukocytapheresis significantly reduced the number of, and increased the time to, clinical relapse in these patients without serious side effects.

https://pubmed.ncbi.nlm.nih.gov/18521900/

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