Laurence Maiden 1, Ken Takeuchi, Rosie Baur, Ingi Bjarnason, John O’Donohue, Ian Forgacs, Guy Chung-Faye, Jeremy Sanderson, Ingvar Bjarnason, Inflamm Bowel Dis. 2008 Oct;14(10):1413-8.
Selective white cell apheresis reduces relapse rates in patients with IBD at significant risk of clinical relapse
This study represents a new approach to the treatment of IBD by targeting a group of asymptomatic patients for treatment who are at significant risk of relapse based on high fecal calprotectin concentrations. Selective leukocytapheresis significantly reduced the number of, and increased the time to, clinical relapse in these patients without serious side effects.
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