Scientific corner

Partial remission of refractory RA after Adacolumn cytapheresis: a case report

L Bazzichi 1T GiulianoA RossiA MazzoniT GrazziniF De FeoC GiacomelliF ScatenaS Bombardieri, Rheumatol Int. 2008 Jan;28(3):295-7.

We report on a female case of rheumatoid arthritis (RA) with hepatitis C virus comorbidity. The patient was treated once weekly over ten consecutive weeks with Adacolumn device. Clinical assessment and HCV-RNA concentration were monitored at weeks-1, 4, 9, 14 and during follow-up over 6 months. At the end of the treatment: the number of tender and swollen joints, patient’s global assessment of disease activity (VAS), physician’s VAS, C-reactive protein (CRP) decreased, respectively; ACR response was >20. This improvement was maintained for over 2 months. At week 38, the patient was re-treated achieving again an ACR response >20.

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