Granulocyte adsorptive apheresis for leg ulcers complicated by rheumatoid arthritis: a report on three successfully treated cases

Shinya Mori MD,Masakazu Nagashima MD,Kazuhiro Yoshida MD,Kouji Yoshino MD,Mikako Aoki MD,Seiji Kawana MD,Ichiro Hirata BSc,Abby Saniabadi PhD, Shinichi Yoshino MD, International journal of Dermatology First published: 06 April 2004

GMA, which depletes activated neutrophils and monocytes/macrophages, appears to be effective for inflammatory skin ulcers which do not respond to conventional medications.

https://onlinelibrary.wiley.com/doi/10.1111/j.1365-4632.2004.01986.x