Scientific corner

Granulocytapheresis versus methylprednisolone in patients with acute ulcerative colitis: 12-month follow up

Giampaolo Bresci 1Giuseppe ParisiAlessandro MazzoniFabrizio ScatenaAlfonso Capria, J Gastroenterol Hepatol. 2008 Nov;23(11):1678-82.

GCAP results were superior to MP for the treatment of UC, even though no statistically significant difference was observed. Side-effects in the GCAP group were significantly lower than in the MP group. This new therapeutic approach seems able to maintain the condition of remission for a longer time after a flare. In fact, the patients who had obtained a remission after a course of CGAP showed fewer relapses during the follow up compared to the patients treated with MP.

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