M P Martínez Montiel, Rev Esp Enferm Dig. 2007 Nov;99(11):623-7.
Granulocytapheresis: Old procedures, new solution
To conclude, granulocytapheresis is a well-tolerated immunomodulating therapy with few side effects and good results in the management of corticoid-dependent or resistant UC, naïve patients, and pediatric subjects; it could be even considered during pregnancy. Results are less clear in CD. Some aspects remain to be elucidated, including session number and duration, and a potential maintenance regimen. Pharmacoeconomics studies are necessary to find the proper place for this technique within
IBD treatment algorithms. Therapy strategies will likely be developed in the future that will combine GMCAP with immunosuppressants and/or biological therapies
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