Midori Hasegawa 1, Chikako Nishii, Nao Kabutan, Masao Kato, Atsushi Ohashi, Shigeru Nakai, Kazutaka Murakami, Makoto Tomita, Kunihiro Nabeshima, Yoshiyuki Hiki, Hisaji Oshima, Satoshi Sugiyama, Ther Apher Dial. 2007 Oct;11(5):337-40.
Effects of Cytapheresis on Tumor Necrosis Factor Receptor and on Expression of CD63 in Myeloperoxidase–Antineutrophil Cytoplasmic Autoantibody-associated Vasculitis
From these results, the inhibition of TNF action and removal of degranulated granulocytes appear to be related to the mechanism whereby cytapheresis can exert a beneficial and therapeutic function in the treatment of MPO-ANCA-associated vasculitis.
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