Scientific corner

Effects of Cytapheresis on Tumor Necrosis Factor Receptor and on Expression of CD63 in Myeloperoxidase–Antineutrophil Cytoplasmic Autoantibody-associated Vasculitis

Midori Hasegawa 1Chikako NishiiNao KabutanMasao KatoAtsushi OhashiShigeru NakaiKazutaka MurakamiMakoto TomitaKunihiro NabeshimaYoshiyuki HikiHisaji OshimaSatoshi Sugiyama, Ther Apher Dial. 2007 Oct;11(5):337-40.

From these results, the inhibition of TNF action and removal of degranulated granulocytes appear to be related to the mechanism whereby cytapheresis can exert a beneficial and therapeutic function in the treatment of MPO-ANCA-associated vasculitis.

https://pubmed.ncbi.nlm.nih.gov/17845393/

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