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Complement Activation Is Involved in Biological Responses to Leukocyte Adsorptive Apheresis

Shoichi Nishise 1Yuji TakedaHiroaki TakedaKatsuyoshi IshihamaTadahisa FukuiSumio Kawata, Dig Dis Sci. 2006 May;51(5):934-41.

These results suggested that bound complement fragment (e.g., C3b) on CA beads plays a central role in granulocyte adsorption to CA beads and that C3a and C5a augment the release of anti-inflammatory substances. We therefore conclude that complement activation is involved in these biological responses of leukocyte apheresis

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