Combination Therapy With Intensive Granulocyte and Monocyte Adsorptive Apheresis Plus Ustekinumab in Patients With Refractory Crohn’s Disease

Satoshi Tanida ¹, Tsutomu Mizoshita ¹, Keiji Ozeki ¹, Takahito Katano ¹, Mamoru Tanaka ¹, Hirotada Nishie ¹, Takaya Shimura ¹, Yasuyuki Okamoto ¹, Eiji Kubota ¹, Hiromi Kataoka ¹, Takashi Joh ¹ , Ther Apher Dial. 2018 Jun;22(3):295-300.

Thus, combination therapy with intensive granulocyte and monocyte absorptive apheresis plus ustekinumab appeared to represent a safe and effective intervention for inducing clinical remission.

https://pubmed.ncbi.nlm.nih.gov/29790276/