Adacolumn® can be used and, in fact, has been used in children. In this country, we have experience in series of patients who have been treated with Adacolumn® when their inflammatory bowel disease has required control without steroids and the results have been good, practically comparable to those of adults and with a fairly similar safety profile as well. International series with a higher number of patients than those published by Spanish groups support these results. So yes, Adacolumn® is a treatment that can be used in children.
References:
- De Carpi JM. Granulocyte and monocyte/macrophage apheresis in paediatric patients with ulcerative colitis: a case series in Spain. Drugs Context. 2022 Mar 9;11:2021-10-6.
- D. Turner, F.M Ruemmele, E. Orlanski-Meyer, A.M Griffiths, J.M. de Carpi et al. Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care-An Evidence-based Guideline From European Crohn’s and Colitis Organization and ESPGHAN j Pediatr Gastroenterol Nutr. 2018 Aug;67(2):257-291.
- H. Rolandsdotter, M. Eberhardson, U.L Fagerberg , Y. Finkel: Granulocyte and Monocyte Apheresis for Induction of Remission in Children With New Onset Inflammatory Bowel Colitis. J Pediatr Gastroenterol Nutr 2018 Jan;66(1):84-89.
- T.Tanaka, T.Yamamoto, K. Sawada, R. Sacco: Treatment options for children and adolescents with Inflammatory Bowel Disease: Is granulomonocytapheresis an effective alternative to drug therapy? Expert Rev Gastroenterol Hepatol. 2017 Aug;11(8):749-758
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