Scientific corner

P442 The additional value of cytapheresis therapy in patients with severe ulcerative colitis treated with oral tacrolimus

S Takahashi, M Colvin, J Toyosawa, M Ishida, T Kagawa, S Kuraoka, Y Aoyama, K Okamoto, I Sakakihara, K Izumikawa, K Yamamoto, S Tanaka, M Matsuura, S Ishikawa, M Wato, T Hasui, T Inaba, Journal of Crohn’s and Colitis, Volume 12, Issue supplement_1, February 2018

Cytapheresis therapy as an additional therapy to oral tacrolimus is effective in patients with severe ulcerative colitis.

)https://academic.oup.com/ecco-jcc/article/12/supplement_1/S328/4808317

Scientific corner

Adacolumn for Hemoperfusion to Deplete Inflammatory Leucocytes as an Alternative or Complementary to Drug Therapy in Patients with Immune Disorders: Basic Mechanisms and Concepts for Therapeutic Efficacy

Jia Huang, Qian Wang, Yongjing Cheng, Yingjuan Chen, Ming Gao, Feng Yang, Bingyao Mu, Rongwei Zhou, Cibo Huang, Altern Ther Health Med. 2020 Jul;26(4):36-42.

This study indicated that LCAP therapy can significantly decrease RA disease activity and is a safe and effective alternative therapy. LCAP therapy significantly reduced serum CXCL16 and serotonin levels, offering a putative mechanism by which it improves the articular symptoms of RA.

https://www.worldscientific.com/doi/10.1142/9789814749084_0031

Scientific corner

Granulo-monocyto apheresis is more effective in mild ulcerative colitis than in moderate to severe disease.

Chiara De Cassan 1, Edoardo Savarino 1, Piero Marson 1, Tiziana Tison 1, Giorgia Hatem 1, Giacomo Carlo Sturniolo 1, Renata D’Incà 1 , World J Gastroenterol. 2014 Dec 7;20(45):17155-62.

Patients with mild UC benefit from GMA more than patients with moderate to severe disease in the short-term period. GMA should be considered a valid therapeutic option in cases of contraindications to immunosuppressants, corticosteroids and/or biologics.

https://pubmed.ncbi.nlm.nih.gov/25493030/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258586/pdf/WJG-20-17155.pdf

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