Scientific corner

Successful remission of ulcerative colitis flare-up during pregnancy with adsorptive granulomonocytapheresis plus tacrolimus

Tomoyoshi Shibuya 1, Keiichi Haga 1, Masato Kamei 1, Koki Okahara 1, Shoko Ito 1, Masahito Takahashi 1, Osamu Nomura 1, Takashi Murakami 1, Masae Makino 1, Tomohiro Kodani 1, Dai Ishikawa 1, Naoto Sakamoto 1, Taro Osada 1, Tatsuo Ogihara 1, Sumio Watanabe 1, Akihito Nagahara 1 , Intest Res. 2018 Jul;16(3):484-488.

Our experience indicates that GMA, as a non-drug therapeutic intervention with a favorable safety profile, plus tacrolimus might be a relevant treatment option for patients with active IBD during pregnancy. A future study of a large cohort of pregnant patients should strengthen our findings.

https://pubmed.ncbi.nlm.nih.gov/30090048/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077305/pdf/ir-16-484.pdf

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