Aya Iwasaki 1, Hiroshi Kawakami 1, Yukari Okubo 1 , Ther Apher Dial. 2018 Aug;22(4):414-416.
Tag : Dermatology
Section scientifique
Granulocyte/Monocyte Adsorption Apheresis as a Novel Therapeutic Approach in the Treatment of an Impetigo Herpetiformis Case.
Section scientifique
Therapeutic depletion of myeloid lineage leukocytes by adsorptive apheresis for psoriatic arthritis: Efficacy of a non-drug intervention for patients refractory to pharmacologics.
Takuro Kanekura 1, Mariko Seishima 2, Masaru Honma 3, Takafumi Etou 4, Hikaru Eto 5, Keiko Okuma 6, Yukari Okubo 7, Yukie Yamaguchi 8, Takeshi Kambara 9, Tomotaka Mabuchi 10, Yasushi Suga 11, Akimichi Morita 12, Kiyofumi Yamanishi 13, Daisuke Tsuruta 14, Kei Itoh 15, Ken Yamaji 16, Shigaku Ikeda 6 , J Dermatol. 2017 Dec;44(12):1353-1359.
This study demonstrates that GMA with the Adacolumn was effective with good safety profile in patients with PsA refractory to pharmacologicals. The results indicate a major role for myeloid leukocytes in the immunopathogenesis of PsA. A large controlled study is warranted to fully evaluate the efficacy of Adacolumn GMA in patients with PsA.
Section scientifique
Impetigo herpetiformis complicated with Intrauterine growth restriction treated successfully with granulocyte and monocyte apheresis
Natsuko Saito-Sasaki 1, Kunio Izu, Yu Sawada, Ryosuke Hino, Ryoji Nakano, Shohei Shimajiri, Izumi Nishimura, Hiromasa Nakamura, Kazumitsu Sugiura, Motonobu Nakamura, Acta Derm Venereol. 2017 Mar 10;97(3):410-411.
Section scientifique
Successful treatment of pyoderma gangrenosum with granulocyte and monocyte adsorption apheresis
Irene Russo 1, Serena Miotto 1, Anna Colpo 2, Piero Marson 2, Tiziana Tison 2, Anna Ferrazzi 1, Mauro Alaibac 1 , Int Wound J. 2017 Feb;14(1):282-284.
The disease was resistant to high doses of methylprednisolone and methotrexate and successfully treated by granulocyte and monocyte adsorption apheresis. To the best of our knowledge, this is the first report on the efficacy of granulocyte and monocyte adsorption apheresis in pyoderma gangrenosum in Europe.
Section scientifique
Sweet’s Syndrome Successfully Treated with Granulocyte and Monocyte Adsorption Apheresis.
Asami Fujii 1, Yoko Mizutani 1, Yuki Hattori 1, Tomoko Takahashi 1, Hidenori Ohnishi 2, Shozo Yoshida 3, Mariko Seishima 1 , Case Rep Dermatol. 2017 May 22;9(2):13-18.
After the first session of GMA therapy, all symptoms including the erythematous lesions and fever were completely resolved, and serum G-CSF level was reduced. Leukocyte count, neutrophil count, serum amyloid A protein, and CRP levels were restored within normal ranges by 2 weeks. Thus, GMA therapy can successfully treat a patient with recurrent Sweet’s syndrome, potentially related to the restoration of elevated serum G-CSF levels.
Section scientifique
Pyoderma Gangrenosum, Acne and Suppurative Hidradenitis Syndrome Treated with Granulocyte and Monocyte Adsorption Apheresis.
Yoko Mizutani 1, Tomomi Okano, Tomoko Takahashi, Hidenori Ohnishi, Osamu Ohara, Akiyo Sano, Mariko Seishima, Acta Derm Venereol. 2017 Feb 8;97(2):275-276.
Section scientifique
Pyoderma Gangrenosum with Ulcerative Colitis Successfully Treated by the Combination of Granulocyte and Monocyte Adsorption Apheresis and Corticosteroids
Masashi Ohno 1, Shigeki Koyama, Mariko Ohara, Kazumi Shimamoto, Yu Kobayashi, Fumiyasu Nakamura, Kazuki Mitsuru, Akira Andoh, Intern Med. 2016;55(1):25-30.
These results suggest that a combination of GMA and corticosteroids might be recommendable to induce the remission of serious PG complicated with UC.
Section scientifique
Pyoderma Gangrenosum with Ulcerative Colitis Successfully Treated by the Combination of Granulocyte and Monocyte Adsorption Apheresis and Corticosteroids
Masashi Ohno 1, Shigeki Koyama, Mariko Ohara, Kazumi Shimamoto, Yu Kobayashi, Fumiyasu Nakamura, Kazuki Mitsuru, Akira Andoh
Intern Med. 2016;55(1):25-30. doi: 10.2169/internalmedicine.55.5422. Epub 2016 Jan 1.
A 36-year-old woman was admitted to our hospital due to swelling and redness of the left lateral malleolus and dorsum of the left foot with severe pain, with a flare-up of ulcerative colitis (UC). A pathologic examination by skin biopsy led to a diagnosis of pyoderma gangrenosum (PG). She was treated with the intravenous administration of prednisolone (60 mg/day), and granulocyte and monocyte adsorption apheresis (GMA) was performed twice-a-week for 5 weeks. This treatment dramatically improved both the skin and colonic mucosal lesions. These results suggest that a combination of GMA and corticosteroids might be recommendable to induce the remission of serious PG complicated with UC.
Section scientifique
Successful treatment of neutrophilic dermatosis in patient with Crohn’s disease with granulocyte and monocyte adsorption apheresis.
Sei-ichiro Motegi 1, Akihiko Uchiyama 1, Sayaka Toki 1, Kazuya Yamada 1, Hiroo Amano 1, Osamu Ishikawa 1 , J Dermatol. 2015 Aug;42(8):836-7.
Section scientifique
Treatment of a patient with neutrophilic dermatoses with granulocyte and monocyte adsorption apheresis: effects on serum cytokine levels.
Koji Kamiya 1, Yumi Aoyama 2, Mariko Kawata 2, Tetsuya Takiguchi 3, Seiko Mitsui 2, Yoshiki Tokura 4, Keiji Iwatsuki 2 , Eur J Dermatol. 2015 Apr;25(2):189-90.
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