Cytokine profile in colonic mucosa of ulcerative colitis correlates with disease activity and response to granulocytapheresis
IL-8 mRNA was significantly increased in inflamed mucosa of UC. Patients with high IL-8 mRNA expression in colonic mucosa despite PSL treatment were responsive to GCAP. Therefore, quantitative measurement of mucosal IL-8 mRNA may be useful in predicting the response to GCAP.
Contact UsFor more informationContact Us