{"id":6853,"date":"2009-09-10T11:07:00","date_gmt":"2009-09-10T11:07:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=6853"},"modified":"2022-02-10T11:14:02","modified_gmt":"2022-02-10T11:14:02","slug":"emerging-drugs-for-the-treatment-of-ulcerative-colitis","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/fr\/professional\/scientific-corner\/emerging-drugs-for-the-treatment-of-ulcerative-colitis\/","title":{"rendered":"Emerging drugs for the treatment of ulcerative colitis"},"content":{"rendered":"
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Luca Pastorelli<\/a>\u00a01<\/a><\/sup>,\u00a0Theresa T Pizarro<\/a>,\u00a0Fabio Cominelli<\/a>,\u00a0Maurizio Vecchi<\/a> Expert Opin Emerg Drugs. <\/a>2009 Sep;14(3):505-21.\u00a0doi: 10.1517\/14728210903146882.<\/p>\n<\/div>\n\n

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Background:\u00a0<\/strong>Ulcerative colitis (UC) is a chronic, relapsing inflammatory disorder of the colon for which the etiology is currently unknown. At present, strategies to treat UC are primarily targeted to control inflammation during active phases of disease as well as maintain remission during quiescence. As such, several unmet needs in the treatment of UC still remain. In recent years, basic research has led to the recognition of several key factors in the pathogenesis of UC, translating into the development of several novel therapeutic agents. Objective:\u00a0<\/strong>The aim of this study is to review emerging therapies that may advance the treatment and improve the overall care of UC patients. Methods:\u00a0<\/strong>An extensive literature search on published manuscripts and meeting proceedings has been performed to provide a comprehensive review of future drug therapies to treat UC. Results\/conclusion:\u00a0<\/strong>The translational application of new discoveries in the basic understanding of UC pathogenesis is continuing and critical for the development of novel treatment strategies. Design of novel biologic therapies to treat UC has the challenge of addressing potential safety issues, while more traditional drugs should be further developed to facilitate patient compliance to treat this chronic, debilitating disease.<\/p>\n<\/div>\n\n

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https:\/\/pubmed.ncbi.nlm.nih.gov\/19656075\/<\/a><\/p>\n<\/div>\n\n

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https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4563345\/<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Luca Pastorelli\u00a01,\u00a0Theresa T Pizarro,\u00a0Fabio Cominelli,\u00a0Maurizio Vecchi Expert Opin Emerg Drugs. 2009 Sep;14(3):505-21.\u00a0doi: 10.1517\/14728210903146882. Background:\u00a0Ulcerative colitis (UC) is a chronic, relapsing inflammatory disorder of the colon for which the etiology is currently unknown. At present, strategies to treat UC are primarily targeted to control inflammation during active phases of disease as well as maintain remission during […]<\/p>\n","protected":false},"template":"","scientific_tags":[520,532,424,74,55,135,306],"class_list":["post-6853","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-chronic","scientific_tags-expert-opinion","scientific_tags-gma","scientific_tags-leukocytapheresis","scientific_tags-steroid-dependent","scientific_tags-steroid-refractory","scientific_tags-ulcerative-colitis"],"acf":[],"yoast_head":"\nEmerging drugs for the treatment of ulcerative colitis - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/emerging-drugs-for-the-treatment-of-ulcerative-colitis\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Emerging drugs for the treatment of ulcerative colitis - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Luca Pastorelli\u00a01,\u00a0Theresa T Pizarro,\u00a0Fabio Cominelli,\u00a0Maurizio Vecchi Expert Opin Emerg Drugs. 2009 Sep;14(3):505-21.\u00a0doi: 10.1517\/14728210903146882. Background:\u00a0Ulcerative colitis (UC) is a chronic, relapsing inflammatory disorder of the colon for which the etiology is currently unknown. At present, strategies to treat UC are primarily targeted to control inflammation during active phases of disease as well as maintain remission during […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/emerging-drugs-for-the-treatment-of-ulcerative-colitis\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2022-02-10T11:14:02+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/emerging-drugs-for-the-treatment-of-ulcerative-colitis\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/emerging-drugs-for-the-treatment-of-ulcerative-colitis\/\",\"name\":\"Emerging drugs for the treatment of ulcerative colitis - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2009-09-10T11:07:00+00:00\",\"dateModified\":\"2022-02-10T11:14:02+00:00\",\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/emerging-drugs-for-the-treatment-of-ulcerative-colitis\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Emerging drugs for the treatment of ulcerative colitis - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/emerging-drugs-for-the-treatment-of-ulcerative-colitis\/","og_locale":"fr_FR","og_type":"article","og_title":"Emerging drugs for the treatment of ulcerative colitis - Adacyte","og_description":"Luca Pastorelli\u00a01,\u00a0Theresa T Pizarro,\u00a0Fabio Cominelli,\u00a0Maurizio Vecchi Expert Opin Emerg Drugs. 2009 Sep;14(3):505-21.\u00a0doi: 10.1517\/14728210903146882. 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