{"id":6815,"date":"2020-07-01T12:49:00","date_gmt":"2020-07-01T12:49:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=6815"},"modified":"2022-02-08T12:53:28","modified_gmt":"2022-02-08T12:53:28","slug":"single-needle-granulocyte-and-monocyte-apheresis-for-ulcerative-colitis-a-retrospective-safety-analysis-2","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/fr\/professional\/scientific-corner\/single-needle-granulocyte-and-monocyte-apheresis-for-ulcerative-colitis-a-retrospective-safety-analysis-2\/","title":{"rendered":"Single Needle Granulocyte and Monocyte  Apheresis for Ulcerative Colitis:  A  Retrospective Safety  Analysis"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Imai+T&amp;cauthor_id=31941846\">Tetsurou Imai<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-1\">1<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yamasaki+H&amp;cauthor_id=31941846\">Hiroshi Yamasaki<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-2\">2<\/a>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-3\">3<\/a>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-4\">4<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Mitsuyama+K&amp;cauthor_id=31941846\">Keiichi Mitsuyama<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-3\">3<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yamaga+O&amp;cauthor_id=31941846\">Osamu Yamaga<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-1\">1<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Sugihara+G&amp;cauthor_id=31941846\">Gaku Sugihara<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-1\">1<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kaida+Y&amp;cauthor_id=31941846\">Yusuke Kaida<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-5\">5<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Shibata+R&amp;cauthor_id=31941846\">Ryo Shibata<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-5\">5<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Hazama+T&amp;cauthor_id=31941846\">Takuma Hazama<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-5\">5<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yoshioka+S&amp;cauthor_id=31941846\">Shinichiro Yoshioka<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-2\">2<\/a>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-3\">3<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Torimura+T&amp;cauthor_id=31941846\">Takuji Torimura<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-2\">2<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Fukami+K&amp;cauthor_id=31941846\">Kei Fukami<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-5\">5<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yamashita+N&amp;cauthor_id=31941846\">Norio Yamashita<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/#affiliation-6\">6<\/a><\/sup><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Kurume Med J. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=%22Kurume+Med+J%22%5Bjour%5D\"><\/a>2020 Jul 1;66(1):1-7.\u00a0doi: 10.2739\/kurumemedj.MS661002.\u00a0Epub 2020 Jan 15.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><strong>Introduction:\u00a0<\/strong>Granulocyte and monocyte apheresis (GMA) is an effective treatment strategy for active ulcerative colitis (UC) in Japan. Single needle (SN) apheresis reduces needle puncture pain in patients because it requires only one puncture site. We evaluated whether single-needle apheresis could be a safe and effective means of reducing patient burden. <strong>Method:\u00a0<\/strong>We performed a retrospective study of active UC patients who were treated with either SN apheresis or conventional double-needle (DN) apheresis at the Kurume university hospital from April 2014 to March 2018. All the patients treated with GMA after September 2016 underwent SN apheresis. Thus, the two groups predominantly belonged to different time periods. We assessed the safety of SN apheresis. <strong>Result:\u00a0<\/strong>Six patients underwent SN apheresis, and 6 underwent DN apheresis. The average time to the start of apheresis was significantly reduced from 23.1 minutes in the case of DN apheresis to 12.6 minutes for SN apheresis. In addition, the number of difficult punctures was significantly reduced with SN apheresis. There were no differences in adverse events between SN and DN apheresis. Treatment benefits, remission rate and disease activity were similar between SN and DN apheresis.<strong>Conclusion:\u00a0<\/strong>SN apheresis reduced both the time to treatment initiation and pain during puncture, and there was no difference in the number of blood clotting episodes as compared with DN. Although further comparative studies are needed, SN apheresis may be a safe alternative for patients to reduce the strain of treatment.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31941846\/<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/www.jstage.jst.go.jp\/article\/kurumemedj\/66\/1\/66_MS661002\/_article\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.jstage.jst.go.jp\/article\/kurumemedj\/66\/1\/66_MS661002\/_article<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Tetsurou Imai\u00a01,\u00a0Hiroshi Yamasaki\u00a02\u00a03\u00a04,\u00a0Keiichi Mitsuyama\u00a03,\u00a0Osamu Yamaga\u00a01,\u00a0Gaku Sugihara\u00a01,\u00a0Yusuke Kaida\u00a05,\u00a0Ryo Shibata\u00a05,\u00a0Takuma Hazama\u00a05,\u00a0Shinichiro Yoshioka\u00a02\u00a03,\u00a0Takuji Torimura\u00a02,\u00a0Kei Fukami\u00a05,\u00a0Norio Yamashita\u00a06 Kurume Med J. 2020 Jul 1;66(1):1-7.\u00a0doi: 10.2739\/kurumemedj.MS661002.\u00a0Epub 2020 Jan 15. Introduction:\u00a0Granulocyte and monocyte apheresis (GMA) is an effective treatment strategy for active ulcerative colitis (UC) in Japan. Single needle (SN) apheresis reduces needle puncture pain in patients because it requires only one [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[424,305,156,63,271,306],"class_list":["post-6815","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-gma","scientific_tags-retrsopective","scientific_tags-safety","scientific_tags-single-needle","scientific_tags-study","scientific_tags-ulcerative-colitis"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Single Needle Granulocyte and Monocyte Apheresis for Ulcerative Colitis: A Retrospective Safety Analysis - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/single-needle-granulocyte-and-monocyte-apheresis-for-ulcerative-colitis-a-retrospective-safety-analysis-2\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Single Needle Granulocyte and Monocyte Apheresis for Ulcerative Colitis: A Retrospective Safety Analysis - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Tetsurou Imai\u00a01,\u00a0Hiroshi Yamasaki\u00a02\u00a03\u00a04,\u00a0Keiichi Mitsuyama\u00a03,\u00a0Osamu Yamaga\u00a01,\u00a0Gaku Sugihara\u00a01,\u00a0Yusuke Kaida\u00a05,\u00a0Ryo Shibata\u00a05,\u00a0Takuma Hazama\u00a05,\u00a0Shinichiro Yoshioka\u00a02\u00a03,\u00a0Takuji Torimura\u00a02,\u00a0Kei Fukami\u00a05,\u00a0Norio Yamashita\u00a06 Kurume Med J. 2020 Jul 1;66(1):1-7.\u00a0doi: 10.2739\/kurumemedj.MS661002.\u00a0Epub 2020 Jan 15. Introduction:\u00a0Granulocyte and monocyte apheresis (GMA) is an effective treatment strategy for active ulcerative colitis (UC) in Japan. Single needle (SN) apheresis reduces needle puncture pain in patients because it requires only one [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/single-needle-granulocyte-and-monocyte-apheresis-for-ulcerative-colitis-a-retrospective-safety-analysis-2\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2022-02-08T12:53:28+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/single-needle-granulocyte-and-monocyte-apheresis-for-ulcerative-colitis-a-retrospective-safety-analysis-2\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/single-needle-granulocyte-and-monocyte-apheresis-for-ulcerative-colitis-a-retrospective-safety-analysis-2\/\",\"name\":\"Single Needle Granulocyte and Monocyte Apheresis for Ulcerative Colitis: A Retrospective Safety Analysis - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2020-07-01T12:49:00+00:00\",\"dateModified\":\"2022-02-08T12:53:28+00:00\",\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/single-needle-granulocyte-and-monocyte-apheresis-for-ulcerative-colitis-a-retrospective-safety-analysis-2\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Single Needle Granulocyte and Monocyte Apheresis for Ulcerative Colitis: A Retrospective Safety Analysis - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/single-needle-granulocyte-and-monocyte-apheresis-for-ulcerative-colitis-a-retrospective-safety-analysis-2\/","og_locale":"fr_FR","og_type":"article","og_title":"Single Needle Granulocyte and Monocyte Apheresis for Ulcerative Colitis: A Retrospective Safety Analysis - Adacyte","og_description":"Tetsurou Imai\u00a01,\u00a0Hiroshi Yamasaki\u00a02\u00a03\u00a04,\u00a0Keiichi Mitsuyama\u00a03,\u00a0Osamu Yamaga\u00a01,\u00a0Gaku Sugihara\u00a01,\u00a0Yusuke Kaida\u00a05,\u00a0Ryo Shibata\u00a05,\u00a0Takuma Hazama\u00a05,\u00a0Shinichiro Yoshioka\u00a02\u00a03,\u00a0Takuji Torimura\u00a02,\u00a0Kei Fukami\u00a05,\u00a0Norio Yamashita\u00a06 Kurume Med J. 2020 Jul 1;66(1):1-7.\u00a0doi: 10.2739\/kurumemedj.MS661002.\u00a0Epub 2020 Jan 15. 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