{"id":5549,"date":"2016-06-30T14:14:00","date_gmt":"2016-06-30T14:14:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=5549"},"modified":"2021-07-12T07:56:34","modified_gmt":"2021-07-12T07:56:34","slug":"pharmacological-and-non-pharmacological-therapeutic-approaches-in-inflammatory-bowel-disease-in-adults","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/fr\/professional\/scientific-corner\/pharmacological-and-non-pharmacological-therapeutic-approaches-in-inflammatory-bowel-disease-in-adults\/","title":{"rendered":"Pharmacological- and non-pharmacological therapeutic approaches in inflammatory bowel disease in adults."},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Leitner+GC&amp;cauthor_id=26855808\">Gerda C Leitner<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26855808\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Vogelsang+H&amp;cauthor_id=26855808\">Harald Vogelsang<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26855808\/#affiliation-1\">1<\/a><\/sup> , World J Gastrointest Pharmacol Ther. 2016 Feb 6;7(1):5-20.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>As therapeutic alternative the main mediators of the disease, namely the activated pro-inflammatory cytokine producing leukocytes can be selectively removed via two apheresis systems (Adacolumn and Cellsorba) in steroid-refractory or dependent cases. Extracorporeal photopheresis results in an increase of regulatory B cells, regulatory CD8(+) T cells and T-regs Type 1. Both types of apheresis were able to induce clinical remission and mucosal healing accompanied by tapering of steroids.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26855808\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/26855808\/<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4734954\/pdf\/WJGPT-7-5.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4734954\/pdf\/WJGPT-7-5.pdf<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Gerda C Leitner&nbsp;1,&nbsp;Harald Vogelsang&nbsp;1 , World J Gastrointest Pharmacol Ther. 2016 Feb 6;7(1):5-20. As therapeutic alternative the main mediators of the disease, namely the activated pro-inflammatory cytokine producing leukocytes can be selectively removed via two apheresis systems (Adacolumn and Cellsorba) in steroid-refractory or dependent cases. Extracorporeal photopheresis results in an increase of regulatory B cells, [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[147,159,358,356,357,306],"class_list":["post-5549","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-clinical-remission","scientific_tags-crohns-disease","scientific_tags-psychological","scientific_tags-step-up","scientific_tags-top-down","scientific_tags-ulcerative-colitis"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pharmacological- and non-pharmacological therapeutic approaches in inflammatory bowel disease in adults. - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pharmacological-and-non-pharmacological-therapeutic-approaches-in-inflammatory-bowel-disease-in-adults\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pharmacological- and non-pharmacological therapeutic approaches in inflammatory bowel disease in adults. - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Gerda C Leitner&nbsp;1,&nbsp;Harald Vogelsang&nbsp;1 , World J Gastrointest Pharmacol Ther. 2016 Feb 6;7(1):5-20. As therapeutic alternative the main mediators of the disease, namely the activated pro-inflammatory cytokine producing leukocytes can be selectively removed via two apheresis systems (Adacolumn and Cellsorba) in steroid-refractory or dependent cases. Extracorporeal photopheresis results in an increase of regulatory B cells, [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pharmacological-and-non-pharmacological-therapeutic-approaches-in-inflammatory-bowel-disease-in-adults\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2021-07-12T07:56:34+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pharmacological-and-non-pharmacological-therapeutic-approaches-in-inflammatory-bowel-disease-in-adults\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pharmacological-and-non-pharmacological-therapeutic-approaches-in-inflammatory-bowel-disease-in-adults\/\",\"name\":\"Pharmacological- and non-pharmacological therapeutic approaches in inflammatory bowel disease in adults. - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2016-06-30T14:14:00+00:00\",\"dateModified\":\"2021-07-12T07:56:34+00:00\",\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pharmacological-and-non-pharmacological-therapeutic-approaches-in-inflammatory-bowel-disease-in-adults\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Pharmacological- and non-pharmacological therapeutic approaches in inflammatory bowel disease in adults. - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pharmacological-and-non-pharmacological-therapeutic-approaches-in-inflammatory-bowel-disease-in-adults\/","og_locale":"fr_FR","og_type":"article","og_title":"Pharmacological- and non-pharmacological therapeutic approaches in inflammatory bowel disease in adults. - Adacyte","og_description":"Gerda C Leitner&nbsp;1,&nbsp;Harald Vogelsang&nbsp;1 , World J Gastrointest Pharmacol Ther. 2016 Feb 6;7(1):5-20. As therapeutic alternative the main mediators of the disease, namely the activated pro-inflammatory cytokine producing leukocytes can be selectively removed via two apheresis systems (Adacolumn and Cellsorba) in steroid-refractory or dependent cases. 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