{"id":4042,"date":"2010-04-21T14:08:00","date_gmt":"2010-04-21T14:08:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=4042"},"modified":"2021-07-09T11:19:38","modified_gmt":"2021-07-09T11:19:38","slug":"selective-depletion-of-peripheral-granulocyte-monocyte-enhances-the-efficacy-of-scheduled-maintenance-infliximab-in-crohns-disease","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/fr\/professional\/scientific-corner\/selective-depletion-of-peripheral-granulocyte-monocyte-enhances-the-efficacy-of-scheduled-maintenance-infliximab-in-crohns-disease\/","title":{"rendered":"Selective depletion of peripheral granulocyte\/monocyte enhances the efficacy of scheduled maintenance infliximab in Crohn&rsquo;s disease"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Fukunaga+K&amp;cauthor_id=20544712\">Ken Fukunaga<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20544712\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yokoyama+Y&amp;cauthor_id=20544712\">Yoko Yokoyama<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kamikozuru+K&amp;cauthor_id=20544712\">Koji Kamikozuru<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yoshida+K&amp;cauthor_id=20544712\">Koji Yoshida<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kikuyama+R&amp;cauthor_id=20544712\">Risa Kikuyama<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Nagase+K&amp;cauthor_id=20544712\">Kazuko Nagase<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Nakamura+S&amp;cauthor_id=20544712\">Shiro Nakamura<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Takei+Y&amp;cauthor_id=20544712\">Yoshiyuki Takei<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Miwa+H&amp;cauthor_id=20544712\">Hiroto Miwa<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Matsumoto+T&amp;cauthor_id=20544712\">Takayuki Matsumoto<\/a>, J Clin Apher. 2010;25(4):226-8.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>IFX appears to induce and maintain remission of CD, but it may lose its efficacy after repeated administration. GMA is safe and by selectively depleting elevated\/activated leukocytes may be a useful adjunct for IFX efficacy.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20544712\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/20544712\/<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Ken Fukunaga&nbsp;1,&nbsp;Yoko Yokoyama,&nbsp;Koji Kamikozuru,&nbsp;Koji Yoshida,&nbsp;Risa Kikuyama,&nbsp;Kazuko Nagase,&nbsp;Shiro Nakamura,&nbsp;Yoshiyuki Takei,&nbsp;Hiroto Miwa,&nbsp;Takayuki Matsumoto, J Clin Apher. 2010;25(4):226-8. IFX appears to induce and maintain remission of CD, but it may lose its efficacy after repeated administration. GMA is safe and by selectively depleting elevated\/activated leukocytes may be a useful adjunct for IFX efficacy. https:\/\/pubmed.ncbi.nlm.nih.gov\/20544712\/<\/p>\n","protected":false},"template":"","scientific_tags":[147,303,109,91,156],"class_list":["post-4042","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-clinical-remission","scientific_tags-combination","scientific_tags-infliximab","scientific_tags-maintenance","scientific_tags-safety"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Selective depletion of peripheral granulocyte\/monocyte enhances the efficacy of scheduled maintenance infliximab in Crohn&#039;s disease - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/selective-depletion-of-peripheral-granulocyte-monocyte-enhances-the-efficacy-of-scheduled-maintenance-infliximab-in-crohns-disease\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Selective depletion of peripheral granulocyte\/monocyte enhances the efficacy of scheduled maintenance infliximab in Crohn&#039;s disease - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Ken Fukunaga&nbsp;1,&nbsp;Yoko Yokoyama,&nbsp;Koji Kamikozuru,&nbsp;Koji Yoshida,&nbsp;Risa Kikuyama,&nbsp;Kazuko Nagase,&nbsp;Shiro Nakamura,&nbsp;Yoshiyuki Takei,&nbsp;Hiroto Miwa,&nbsp;Takayuki Matsumoto, J Clin Apher. 2010;25(4):226-8. IFX appears to induce and maintain remission of CD, but it may lose its efficacy after repeated administration. GMA is safe and by selectively depleting elevated\/activated leukocytes may be a useful adjunct for IFX efficacy. https:\/\/pubmed.ncbi.nlm.nih.gov\/20544712\/\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/selective-depletion-of-peripheral-granulocyte-monocyte-enhances-the-efficacy-of-scheduled-maintenance-infliximab-in-crohns-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2021-07-09T11:19:38+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/selective-depletion-of-peripheral-granulocyte-monocyte-enhances-the-efficacy-of-scheduled-maintenance-infliximab-in-crohns-disease\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/selective-depletion-of-peripheral-granulocyte-monocyte-enhances-the-efficacy-of-scheduled-maintenance-infliximab-in-crohns-disease\/\",\"name\":\"Selective depletion of peripheral granulocyte\/monocyte enhances the efficacy of scheduled maintenance infliximab in Crohn's disease - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2010-04-21T14:08:00+00:00\",\"dateModified\":\"2021-07-09T11:19:38+00:00\",\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/selective-depletion-of-peripheral-granulocyte-monocyte-enhances-the-efficacy-of-scheduled-maintenance-infliximab-in-crohns-disease\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Selective depletion of peripheral granulocyte\/monocyte enhances the efficacy of scheduled maintenance infliximab in Crohn's disease - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/selective-depletion-of-peripheral-granulocyte-monocyte-enhances-the-efficacy-of-scheduled-maintenance-infliximab-in-crohns-disease\/","og_locale":"fr_FR","og_type":"article","og_title":"Selective depletion of peripheral granulocyte\/monocyte enhances the efficacy of scheduled maintenance infliximab in Crohn's disease - Adacyte","og_description":"Ken Fukunaga&nbsp;1,&nbsp;Yoko Yokoyama,&nbsp;Koji Kamikozuru,&nbsp;Koji Yoshida,&nbsp;Risa Kikuyama,&nbsp;Kazuko Nagase,&nbsp;Shiro Nakamura,&nbsp;Yoshiyuki Takei,&nbsp;Hiroto Miwa,&nbsp;Takayuki Matsumoto, J Clin Apher. 2010;25(4):226-8. 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