{"id":4035,"date":"2011-04-11T13:58:00","date_gmt":"2011-04-11T13:58:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=4035"},"modified":"2021-07-09T11:22:18","modified_gmt":"2021-07-09T11:22:18","slug":"treatment-of-refractory-crohns-disease-by-intensive-granulocyte-and-monocyte-adsorption-apheresis-a-report-on-two-drug-refractory-cases","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/fr\/professional\/scientific-corner\/treatment-of-refractory-crohns-disease-by-intensive-granulocyte-and-monocyte-adsorption-apheresis-a-report-on-two-drug-refractory-cases\/","title":{"rendered":"Treatment of refractory Crohn&rsquo;s disease by intensive granulocyte and monocyte adsorption apheresis: a report on two drug refractory cases"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kato+S&amp;cauthor_id=21804287\">Shingo Kato<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21804287\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kani+K&amp;cauthor_id=21804287\">Kazuhito Kani<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Takabayashi+H&amp;cauthor_id=21804287\">Hidehiko Takabayashi<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yamamoto+R&amp;cauthor_id=21804287\">Ryuichi Yamamoto<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ogawa+T&amp;cauthor_id=21804287\">Tomonari Ogawa<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Matsuda+A&amp;cauthor_id=21804287\">Akihiko Matsuda<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yakabi+K&amp;cauthor_id=21804287\">Koji Yakabi<\/a>, Intern ed. 2011;50(15):1591-3.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Granulocyte and monocyte adsorption apheresis (GMA) is one therapeutic option for induction of remission in patients with inflammatory bowel diseases. Recently intensive GMA (2 sessions per week) was reported to be strikingly better than weekly GMA, both in remission rate and time to remission. Here we report two cases of Crohn&rsquo;s disease refractory to weekly GMA who responded to intensive GMA. One patient had not received immunosuppressive therapy while the other had been refractory to combination therapy with infliximab and azathioprine. Intensive GMA induced remission in these 2 patients. Intensive GMA may represent a therapeutic choice for remission induction and maintenance with infliximab.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21804287\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/21804287\/<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/50\/15\/50_15_1591\/_pdf\/-char\/en\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.jstage.jst.go.jp\/article\/internalmedicine\/50\/15\/50_15_1591\/_pdf\/-char\/en<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Shingo Kato&nbsp;1,&nbsp;Kazuhito Kani,&nbsp;Hidehiko Takabayashi,&nbsp;Ryuichi Yamamoto,&nbsp;Tomonari Ogawa,&nbsp;Akihiko Matsuda,&nbsp;Koji Yakabi, Intern ed. 2011;50(15):1591-3. Granulocyte and monocyte adsorption apheresis (GMA) is one therapeutic option for induction of remission in patients with inflammatory bowel diseases. Recently intensive GMA (2 sessions per week) was reported to be strikingly better than weekly GMA, both in remission rate and time to remission. [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[276,147,53],"class_list":["post-4035","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-cases","scientific_tags-clinical-remission","scientific_tags-refractory-patients"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Treatment of refractory Crohn&#039;s disease by intensive granulocyte and monocyte adsorption apheresis: a report on two drug refractory cases - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/treatment-of-refractory-crohns-disease-by-intensive-granulocyte-and-monocyte-adsorption-apheresis-a-report-on-two-drug-refractory-cases\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Treatment of refractory Crohn&#039;s disease by intensive granulocyte and monocyte adsorption apheresis: a report on two drug refractory cases - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Shingo Kato&nbsp;1,&nbsp;Kazuhito Kani,&nbsp;Hidehiko Takabayashi,&nbsp;Ryuichi Yamamoto,&nbsp;Tomonari Ogawa,&nbsp;Akihiko Matsuda,&nbsp;Koji Yakabi, Intern ed. 2011;50(15):1591-3. Granulocyte and monocyte adsorption apheresis (GMA) is one therapeutic option for induction of remission in patients with inflammatory bowel diseases. Recently intensive GMA (2 sessions per week) was reported to be strikingly better than weekly GMA, both in remission rate and time to remission. 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Granulocyte and monocyte adsorption apheresis (GMA) is one therapeutic option for induction of remission in patients with inflammatory bowel diseases. Recently intensive GMA (2 sessions per week) was reported to be strikingly better than weekly GMA, both in remission rate and time to remission. 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