{"id":3944,"date":"2017-04-27T08:18:00","date_gmt":"2017-04-27T08:18:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=3944"},"modified":"2021-07-12T07:59:19","modified_gmt":"2021-07-12T07:59:19","slug":"efficacy-of-granulocyte-and-monocyte-apheresis-for-antibiotic-refractory-pouchitis-after-proctocolectomy-for-ulcerative-colitis-an-open-label-prospective-multicentre-study","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/fr\/professional\/scientific-corner\/efficacy-of-granulocyte-and-monocyte-apheresis-for-antibiotic-refractory-pouchitis-after-proctocolectomy-for-ulcerative-colitis-an-open-label-prospective-multicentre-study\/","title":{"rendered":"Efficacy of granulocyte and monocyte apheresis for antibiotic-refractory pouchitis after proctocolectomy for ulcerative colitis: an open-label, prospective, multicentre study"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yamamoto+T&amp;cauthor_id=28203278\">Takayuki Yamamoto<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Tanaka+T&amp;cauthor_id=28203278\">Toshiaki Tanaka<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/#affiliation-2\">2<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yokoyama+T&amp;cauthor_id=28203278\">Tadashi Yokoyama<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/#affiliation-3\">3<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Shimoyama+T&amp;cauthor_id=28203278\">Takahiro Shimoyama<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ikeuchi+H&amp;cauthor_id=28203278\">Hiroki Ikeuchi<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/#affiliation-4\">4<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Uchino+M&amp;cauthor_id=28203278\">Motoi Uchino<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/#affiliation-4\">4<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Watanabe+T&amp;cauthor_id=28203278\">Toshiaki Watanabe<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/#affiliation-5\">5<\/a><\/sup> , Therap Adv Gastroenterol. 2017 Feb;10(2):199-206.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>GMA has a good safety profile, but its efficacy appears to be limited in the management of chronic refractory pouchitis. However, a large controlled study should be conducted to evaluate the efficacy of GMA therapy in patients with pouchitis at an earlier clinical stage, before the disease has become refractory to conventional medical therapy.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/28203278\/<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5298477\/pdf\/10.1177_1756283X16679348.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5298477\/pdf\/10.1177_1756283X16679348.pdf<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Takayuki Yamamoto&nbsp;1,&nbsp;Toshiaki Tanaka&nbsp;2,&nbsp;Tadashi Yokoyama&nbsp;3,&nbsp;Takahiro Shimoyama&nbsp;1,&nbsp;Hiroki Ikeuchi&nbsp;4,&nbsp;Motoi Uchino&nbsp;4,&nbsp;Toshiaki Watanabe&nbsp;5 , Therap Adv Gastroenterol. 2017 Feb;10(2):199-206. GMA has a good safety profile, but its efficacy appears to be limited in the management of chronic refractory pouchitis. However, a large controlled study should be conducted to evaluate the efficacy of GMA therapy in patients with pouchitis at an [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[93,330,86,96,94,95,97,156],"class_list":["post-3944","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-antibiotic","scientific_tags-clinical-trial","scientific_tags-multicentre","scientific_tags-open-label","scientific_tags-pouchitis","scientific_tags-proctocolectomy","scientific_tags-prospective","scientific_tags-safety"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Efficacy of granulocyte and monocyte apheresis for antibiotic-refractory pouchitis after proctocolectomy for ulcerative colitis: an open-label, prospective, multicentre study - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/efficacy-of-granulocyte-and-monocyte-apheresis-for-antibiotic-refractory-pouchitis-after-proctocolectomy-for-ulcerative-colitis-an-open-label-prospective-multicentre-study\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Efficacy of granulocyte and monocyte apheresis for antibiotic-refractory pouchitis after proctocolectomy for ulcerative colitis: an open-label, prospective, multicentre study - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Takayuki Yamamoto&nbsp;1,&nbsp;Toshiaki Tanaka&nbsp;2,&nbsp;Tadashi Yokoyama&nbsp;3,&nbsp;Takahiro Shimoyama&nbsp;1,&nbsp;Hiroki Ikeuchi&nbsp;4,&nbsp;Motoi Uchino&nbsp;4,&nbsp;Toshiaki Watanabe&nbsp;5 , Therap Adv Gastroenterol. 2017 Feb;10(2):199-206. GMA has a good safety profile, but its efficacy appears to be limited in the management of chronic refractory pouchitis. 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