{"id":11057,"date":"2025-05-14T11:15:00","date_gmt":"2025-05-14T09:15:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=11057"},"modified":"2025-08-08T11:20:05","modified_gmt":"2025-08-08T09:20:05","slug":"evolving-trends-in-pediatric-inflammatory-bowel-disease-management-in-japan-a-decade-of-nationwide-data","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/fr\/professional\/scientific-corner\/evolving-trends-in-pediatric-inflammatory-bowel-disease-management-in-japan-a-decade-of-nationwide-data\/","title":{"rendered":"Evolving Trends in Pediatric Inflammatory Bowel Disease Management in Japan: A Decade of Nationwide Data"},"content":{"rendered":"
\n

Miki Urushiyama<\/a>\u00a01<\/a><\/sup>,\u00a0Kunio Tarasawa<\/a>\u00a02<\/a><\/sup>,\u00a0Rintaro Moroi<\/a>\u00a01<\/a><\/sup>,\u00a0Hideya Iwaki<\/a>\u00a01<\/a><\/sup>,\u00a0Yusuke Hoshi<\/a>\u00a03<\/a><\/sup>,\u00a0Hiroshi Nagai<\/a>\u00a01<\/a><\/sup>,\u00a0Yusuke Shimoyama<\/a>\u00a01<\/a><\/sup>,\u00a0Takeo Naito<\/a>\u00a01<\/a><\/sup>,\u00a0Fumihiko Kakuta<\/a>\u00a03<\/a><\/sup>,\u00a0Hisashi Shiga<\/a>\u00a01<\/a><\/sup>,\u00a0Shin Hamada<\/a>\u00a01<\/a><\/sup>,\u00a0Yoichi Kakuta<\/a>\u00a01<\/a><\/sup>,\u00a0Kiyohide Fushimi<\/a>\u00a04<\/a><\/sup>,\u00a0Yoshitaka Kinouchi<\/a>\u00a01<\/a><\/sup>,\u00a0Daiki Abukawa<\/a>\u00a03<\/a><\/sup>,\u00a0Kenji Fujimori<\/a>\u00a02<\/a><\/sup>,\u00a0Atsushi Masamune<\/a>\u00a01<\/a><\/sup><\/p>\n<\/div>\n\n

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JGH Open. .\u00a02025 May 14;9(5):e70175.\u00a0doi: 10.1002\/jgh3.70175.\u00a0eCollection 2025 May.<\/p>\n<\/div>\n\n

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Aims: <\/strong>This study aimed to investigate the trends in pediatric inflammatory bowel diseases (IBD) management in Japan over the past decade.<\/p>\n<\/div>\n\n

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Methods: <\/strong>We retrospectively analyzed data from Japan’s nationwide database from 2012 to 2022. Patients aged \u2264 15 years diagnosed with Crohn’s disease (CD) or ulcerative colitis (UC) were included. Trends in the use of biologics, capsule endoscopy, total parenteral nutrition (TPN), elemental diets, surgery, and granulocyte and monocyte apheresis (GMA) were examined using the Cochrane-Armitage and Jonckheere-Terpstra trend tests.<\/p>\n<\/div>\n\n

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Results: <\/strong>Among the 8037 and 6153 pediatric UC and CD admissions, respectively, the use of biologics increased significantly (CD: from 46.0% to 53.6%; UC: from 15.0% to 33.0%, p<\/em> < 0.0001). The use of capsule endoscopy in pediatric patients with CD increased markedly from 6.6% to 16.7% (p<\/em> < 0.0001), whereas TPN use decreased from 8.4% to 3.0% (p<\/em> < 0.0001). Surgery rates for patients with CD remained at approximately 5%, whereas those for patients with UC decreased (from 3.7% to 1.7%, p<\/em> = 0.002). Elemental diets for pediatric patients with CD increased (from 54.4% to 66.2%, p<\/em> < 0.0001). The use of GMA decreased significantly in patients with UC (from 12.1% to 2.7%, p<\/em> < 0.0001).<\/p>\n<\/div>\n\n

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Conclusion: <\/strong>The use of biologics and capsule endoscopy has increased in pediatric patients with IBD, whereas the use of more invasive treatments has decreased. These trends suggest a shift toward less invasive and more targeted therapeutic strategies in managing pediatric patients with IBD in Japan.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Miki Urushiyama\u00a01,\u00a0Kunio Tarasawa\u00a02,\u00a0Rintaro Moroi\u00a01,\u00a0Hideya Iwaki\u00a01,\u00a0Yusuke Hoshi\u00a03,\u00a0Hiroshi Nagai\u00a01,\u00a0Yusuke Shimoyama\u00a01,\u00a0Takeo Naito\u00a01,\u00a0Fumihiko Kakuta\u00a03,\u00a0Hisashi Shiga\u00a01,\u00a0Shin Hamada\u00a01,\u00a0Yoichi Kakuta\u00a01,\u00a0Kiyohide Fushimi\u00a04,\u00a0Yoshitaka Kinouchi\u00a01,\u00a0Daiki Abukawa\u00a03,\u00a0Kenji Fujimori\u00a02,\u00a0Atsushi Masamune\u00a01 JGH Open. .\u00a02025 May 14;9(5):e70175.\u00a0doi: 10.1002\/jgh3.70175.\u00a0eCollection 2025 May. Aims: This study aimed to investigate the trends in pediatric inflammatory bowel diseases (IBD) management in Japan over the past decade. Methods: We retrospectively analyzed data from Japan’s nationwide database from […]<\/p>\n","protected":false},"template":"","scientific_tags":[134,875,409,424,426,765,874,405,48,811,876],"class_list":["post-11057","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-biologics","scientific_tags-diet","scientific_tags-endoscopy","scientific_tags-gma","scientific_tags-ibd","scientific_tags-japan","scientific_tags-parenteral-nutrition","scientific_tags-pediatric","scientific_tags-retrospective","scientific_tags-surgery","scientific_tags-trends"],"acf":[],"yoast_head":"\nEvolving Trends in Pediatric Inflammatory Bowel Disease Management in Japan: A Decade of Nationwide Data - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/evolving-trends-in-pediatric-inflammatory-bowel-disease-management-in-japan-a-decade-of-nationwide-data\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Evolving Trends in Pediatric Inflammatory Bowel Disease Management in Japan: A Decade of Nationwide Data - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Miki Urushiyama\u00a01,\u00a0Kunio Tarasawa\u00a02,\u00a0Rintaro Moroi\u00a01,\u00a0Hideya Iwaki\u00a01,\u00a0Yusuke Hoshi\u00a03,\u00a0Hiroshi Nagai\u00a01,\u00a0Yusuke Shimoyama\u00a01,\u00a0Takeo Naito\u00a01,\u00a0Fumihiko Kakuta\u00a03,\u00a0Hisashi Shiga\u00a01,\u00a0Shin Hamada\u00a01,\u00a0Yoichi Kakuta\u00a01,\u00a0Kiyohide Fushimi\u00a04,\u00a0Yoshitaka Kinouchi\u00a01,\u00a0Daiki Abukawa\u00a03,\u00a0Kenji Fujimori\u00a02,\u00a0Atsushi Masamune\u00a01 JGH Open. .\u00a02025 May 14;9(5):e70175.\u00a0doi: 10.1002\/jgh3.70175.\u00a0eCollection 2025 May. Aims: This study aimed to investigate the trends in pediatric inflammatory bowel diseases (IBD) management in Japan over the past decade. 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