{"id":7140,"date":"2008-10-01T11:53:00","date_gmt":"2008-10-01T11:53:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=7140"},"modified":"2022-04-01T12:13:59","modified_gmt":"2022-04-01T12:13:59","slug":"leukocytapheresis-in-a-girl-with-severe-ulcerative-colitis-refractory-to-corticosteroids-infliximab-and-cyclosporine-a","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/es\/professional\/scientific-corner\/leukocytapheresis-in-a-girl-with-severe-ulcerative-colitis-refractory-to-corticosteroids-infliximab-and-cyclosporine-a\/","title":{"rendered":"Leukocytapheresis in a girl with severe ulcerative colitis refractory to corticosteroids, infliximab, and cyclosporine A"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Dittrich+K&amp;cauthor_id=18421764\">Katalin Dittrich<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Richter+M&amp;cauthor_id=18421764\">Markus Richter<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Rascher+W&amp;cauthor_id=18421764\">Wolfgang Rascher<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=K%C3%B6hler+H&amp;cauthor_id=18421764\">Henrik K\u00f6hler<\/a> Inflamm Bowel Dis <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=%22Inflamm+Bowel+Dis%22%5Bjour%5D\"><\/a>2008 Oct;14(10):1466-7.\u00a0doi: 10.1002\/ibd.20464.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Although medical therapy remains the first-line treatment for UC, colectomy may be required for patients with severe medically refractory disease.  Leukocytapheresis (LCAP) has been reported as a new line of therapy in<br>patients with UC. Only 2 pediatric case series, not including patients on immunosuppressive therapy or biologicals, treated with granulocytapheresis have been reported.  The patient reported by us is the youngest to the best of our knowledge in which this LCAP technique was used . She had severe colitis refractory to corticosteroids, infliximab and yclosporine A. We were able to avoid colectomy and the procedure was well tolerated.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18421764\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/18421764\/<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Katalin Dittrich,\u00a0Markus Richter,\u00a0Wolfgang Rascher,\u00a0Henrik K\u00f6hler Inflamm Bowel Dis 2008 Oct;14(10):1466-7.\u00a0doi: 10.1002\/ibd.20464. Although medical therapy remains the first-line treatment for UC, colectomy may be required for patients with severe medically refractory disease. Leukocytapheresis (LCAP) has been reported as a new line of therapy inpatients with UC. Only 2 pediatric case series, not including patients on immunosuppressive [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[147,138,602,424,109,465,74,405,156,559,527,306],"class_list":["post-7140","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-clinical-remission","scientific_tags-corticosteroids","scientific_tags-cyclosporine-a","scientific_tags-gma","scientific_tags-infliximab","scientific_tags-intensive","scientific_tags-leukocytapheresis","scientific_tags-pediatric","scientific_tags-safety","scientific_tags-severe","scientific_tags-steroid","scientific_tags-ulcerative-colitis"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Leukocytapheresis in a girl with severe ulcerative colitis refractory to corticosteroids, infliximab, and cyclosporine A - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/leukocytapheresis-in-a-girl-with-severe-ulcerative-colitis-refractory-to-corticosteroids-infliximab-and-cyclosporine-a\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Leukocytapheresis in a girl with severe ulcerative colitis refractory to corticosteroids, infliximab, and cyclosporine A - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Katalin Dittrich,\u00a0Markus Richter,\u00a0Wolfgang Rascher,\u00a0Henrik K\u00f6hler Inflamm Bowel Dis 2008 Oct;14(10):1466-7.\u00a0doi: 10.1002\/ibd.20464. Although medical therapy remains the first-line treatment for UC, colectomy may be required for patients with severe medically refractory disease. Leukocytapheresis (LCAP) has been reported as a new line of therapy inpatients with UC. Only 2 pediatric case series, not including patients on immunosuppressive [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/leukocytapheresis-in-a-girl-with-severe-ulcerative-colitis-refractory-to-corticosteroids-infliximab-and-cyclosporine-a\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2022-04-01T12:13:59+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/leukocytapheresis-in-a-girl-with-severe-ulcerative-colitis-refractory-to-corticosteroids-infliximab-and-cyclosporine-a\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/leukocytapheresis-in-a-girl-with-severe-ulcerative-colitis-refractory-to-corticosteroids-infliximab-and-cyclosporine-a\/\",\"name\":\"Leukocytapheresis in a girl with severe ulcerative colitis refractory to corticosteroids, infliximab, and cyclosporine A - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2008-10-01T11:53:00+00:00\",\"dateModified\":\"2022-04-01T12:13:59+00:00\",\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/leukocytapheresis-in-a-girl-with-severe-ulcerative-colitis-refractory-to-corticosteroids-infliximab-and-cyclosporine-a\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Leukocytapheresis in a girl with severe ulcerative colitis refractory to corticosteroids, infliximab, and cyclosporine A - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/leukocytapheresis-in-a-girl-with-severe-ulcerative-colitis-refractory-to-corticosteroids-infliximab-and-cyclosporine-a\/","og_locale":"es_ES","og_type":"article","og_title":"Leukocytapheresis in a girl with severe ulcerative colitis refractory to corticosteroids, infliximab, and cyclosporine A - Adacyte","og_description":"Katalin Dittrich,\u00a0Markus Richter,\u00a0Wolfgang Rascher,\u00a0Henrik K\u00f6hler Inflamm Bowel Dis 2008 Oct;14(10):1466-7.\u00a0doi: 10.1002\/ibd.20464. Although medical therapy remains the first-line treatment for UC, colectomy may be required for patients with severe medically refractory disease. Leukocytapheresis (LCAP) has been reported as a new line of therapy inpatients with UC. 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