{"id":6626,"date":"2006-08-28T14:17:00","date_gmt":"2006-08-28T14:17:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=6626"},"modified":"2022-01-28T14:20:55","modified_gmt":"2022-01-28T14:20:55","slug":"therapeutic-efficacy-of-leukocytapheresis-in-a-pregnant-woman-with-severe-active-ulcerative-colitis","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/es\/professional\/scientific-corner\/therapeutic-efficacy-of-leukocytapheresis-in-a-pregnant-woman-with-severe-active-ulcerative-colitis\/","title":{"rendered":"Therapeutic efficacy of leukocytapheresis in a pregnant woman with severe active ulcerative colitis"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Okada+H&amp;cauthor_id=16940730\">H Okada<\/a><sup>\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16940730\/#affiliation-1\">1<\/a><\/sup>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Makidono+C&amp;cauthor_id=16940730\">C Makidono<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Takenaka+R&amp;cauthor_id=16940730\">R Takenaka<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Hiraoka+S&amp;cauthor_id=16940730\">S Hiraoka<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Fujiwara+A&amp;cauthor_id=16940730\">A Fujiwara<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kato+J&amp;cauthor_id=16940730\">J Kato<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kawahara+Y&amp;cauthor_id=16940730\">Y Kawahara<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kawamoto+H&amp;cauthor_id=16940730\">H Kawamoto<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Mizuno+M&amp;cauthor_id=16940730\">M Mizuno<\/a>,\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Shiratori+Y&amp;cauthor_id=16940730\">Y Shiratori<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Digestion <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=%22Digestion%22%5Bjour%5D\"><\/a>2006;74(1):15-8.\u00a0doi: 10.1159\/000095478.\u00a0Epub 2006 Aug 29.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><strong>Leukocytapheresis has recently been used to induce remission in patients with ulcerative colitis (UC) who fail to respond to corticosteroids. We could not find a report in the literature on leukocytapheresis for UC with gestational exacerbation. We have recently encountered this unique condition and report the details here. A 30-year-old Japanese woman with left-sided severe UC was corticosteroid-dependent and had recurrence of the active disease during tapering of corticosteroid. She declined any dose increase and the use of any immunosuppressive agent because she was in the 13th week of pregnancy. Then, concomitant leukocytapheresis was performed without increasing the corticosteroid dose. Recovery was rapid and dramatic. Mucous and bloody stool decreased after the first session, and she had remission 2 weeks later. She underwent a total of four sessions without complications. After 6 weeks, she was discharged from our hospital and underwent maintenance treatment as an outpatient with mesalazine and corticosteroid tapering. Subsequently, she gave birth to a healthy baby girl by an uncomplicated vaginal delivery while keeping the remitted stage of UC.<\/strong><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16940730\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/16940730\/<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>H Okada\u00a01,\u00a0C Makidono,\u00a0R Takenaka,\u00a0S Hiraoka,\u00a0A Fujiwara,\u00a0J Kato,\u00a0Y Kawahara,\u00a0H Kawamoto,\u00a0M Mizuno,\u00a0Y Shiratori Digestion 2006;74(1):15-8.\u00a0doi: 10.1159\/000095478.\u00a0Epub 2006 Aug 29. Leukocytapheresis has recently been used to induce remission in patients with ulcerative colitis (UC) who fail to respond to corticosteroids. We could not find a report in the literature on leukocytapheresis for UC with gestational exacerbation. We have [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[424,74,72,311,55,306],"class_list":["post-6626","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-gma","scientific_tags-leukocytapheresis","scientific_tags-pregnancy","scientific_tags-special-situations","scientific_tags-steroid-dependent","scientific_tags-ulcerative-colitis"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Therapeutic efficacy of leukocytapheresis in a pregnant woman with severe active ulcerative colitis - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/therapeutic-efficacy-of-leukocytapheresis-in-a-pregnant-woman-with-severe-active-ulcerative-colitis\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Therapeutic efficacy of leukocytapheresis in a pregnant woman with severe active ulcerative colitis - Adacyte\" \/>\n<meta property=\"og:description\" content=\"H Okada\u00a01,\u00a0C Makidono,\u00a0R Takenaka,\u00a0S Hiraoka,\u00a0A Fujiwara,\u00a0J Kato,\u00a0Y Kawahara,\u00a0H Kawamoto,\u00a0M Mizuno,\u00a0Y Shiratori Digestion 2006;74(1):15-8.\u00a0doi: 10.1159\/000095478.\u00a0Epub 2006 Aug 29. Leukocytapheresis has recently been used to induce remission in patients with ulcerative colitis (UC) who fail to respond to corticosteroids. We could not find a report in the literature on leukocytapheresis for UC with gestational exacerbation. We have [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/therapeutic-efficacy-of-leukocytapheresis-in-a-pregnant-woman-with-severe-active-ulcerative-colitis\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2022-01-28T14:20:55+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/therapeutic-efficacy-of-leukocytapheresis-in-a-pregnant-woman-with-severe-active-ulcerative-colitis\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/therapeutic-efficacy-of-leukocytapheresis-in-a-pregnant-woman-with-severe-active-ulcerative-colitis\/\",\"name\":\"Therapeutic efficacy of leukocytapheresis in a pregnant woman with severe active ulcerative colitis - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2006-08-28T14:17:00+00:00\",\"dateModified\":\"2022-01-28T14:20:55+00:00\",\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/therapeutic-efficacy-of-leukocytapheresis-in-a-pregnant-woman-with-severe-active-ulcerative-colitis\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Therapeutic efficacy of leukocytapheresis in a pregnant woman with severe active ulcerative colitis - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/therapeutic-efficacy-of-leukocytapheresis-in-a-pregnant-woman-with-severe-active-ulcerative-colitis\/","og_locale":"es_ES","og_type":"article","og_title":"Therapeutic efficacy of leukocytapheresis in a pregnant woman with severe active ulcerative colitis - Adacyte","og_description":"H Okada\u00a01,\u00a0C Makidono,\u00a0R Takenaka,\u00a0S Hiraoka,\u00a0A Fujiwara,\u00a0J Kato,\u00a0Y Kawahara,\u00a0H Kawamoto,\u00a0M Mizuno,\u00a0Y Shiratori Digestion 2006;74(1):15-8.\u00a0doi: 10.1159\/000095478.\u00a0Epub 2006 Aug 29. 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