{"id":6508,"date":"2007-12-14T14:31:00","date_gmt":"2007-12-14T14:31:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=6508"},"modified":"2022-11-17T14:51:11","modified_gmt":"2022-11-17T14:51:11","slug":"pyoderma-gangrenosum-a-review","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/es\/professional\/scientific-corner\/pyoderma-gangrenosum-a-review\/","title":{"rendered":"Pyoderma gangrenosum \u2013 a review"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/ojrd.biomedcentral.com\/articles\/10.1186\/1750-1172-2-19#auth-Uwe-Wollina\">Uwe Wollina<\/a>, <a href=\"https:\/\/ojrd.biomedcentral.com\/\"><em>Orphanet Journal of Rare Diseases<\/em><\/a>&nbsp;<strong>volume&nbsp;2<\/strong>, Article&nbsp;number:&nbsp;19&nbsp;(2007)<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Pyoderma gangrenosum (PG) is a rare noninfectious neutrophilic dermatosis. Clinically it starts with sterile pustules that rapidly progress and turn into painful ulcers of variable depth and size with undermined violaceous borders. The legs are most commonly affected but other parts of the skin and mucous membranes may also be involved. Course can be mild or malignant, chronic or relapsing with remarkable morbidity. In many cases PG is associated with an underlying disease, most commonly inflammatory bowel disease, rheumatic or haematological disease and malignancy. Diagnosis of PG is based on history of an underlying disease, typical clinical presentation, histopathology, and exclusion of other diseases that would lead to a similar appearance. The peak of incidence occurs between the ages of 20 to 50 years with women being more often affected than men. Aetiology has not been clearly determined yet.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/ojrd.biomedcentral.com\/articles\/10.1186\/1750-1172-2-19\">Pyoderma gangrenosum \u2013 a review | Orphanet Journal of Rare Diseases | Full Text (biomedcentral.com)<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Uwe Wollina, Orphanet Journal of Rare Diseases&nbsp;volume&nbsp;2, Article&nbsp;number:&nbsp;19&nbsp;(2007) Pyoderma gangrenosum (PG) is a rare noninfectious neutrophilic dermatosis. Clinically it starts with sterile pustules that rapidly progress and turn into painful ulcers of variable depth and size with undermined violaceous borders. The legs are most commonly affected but other parts of the skin and mucous membranes [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[307,526,374,112,115,463],"class_list":["post-6508","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-dermatology","scientific_tags-eim","scientific_tags-inflammatory-bowel-disease","scientific_tags-neutrophilic-dermatosis","scientific_tags-pyoderma-gangrenosum","scientific_tags-skin"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pyoderma gangrenosum \u2013 a review - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pyoderma-gangrenosum-a-review\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pyoderma gangrenosum \u2013 a review - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Uwe Wollina, Orphanet Journal of Rare Diseases&nbsp;volume&nbsp;2, Article&nbsp;number:&nbsp;19&nbsp;(2007) Pyoderma gangrenosum (PG) is a rare noninfectious neutrophilic dermatosis. Clinically it starts with sterile pustules that rapidly progress and turn into painful ulcers of variable depth and size with undermined violaceous borders. The legs are most commonly affected but other parts of the skin and mucous membranes [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pyoderma-gangrenosum-a-review\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2022-11-17T14:51:11+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pyoderma-gangrenosum-a-review\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pyoderma-gangrenosum-a-review\/\",\"name\":\"Pyoderma gangrenosum \u2013 a review - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2007-12-14T14:31:00+00:00\",\"dateModified\":\"2022-11-17T14:51:11+00:00\",\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pyoderma-gangrenosum-a-review\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Pyoderma gangrenosum \u2013 a review - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/pyoderma-gangrenosum-a-review\/","og_locale":"es_ES","og_type":"article","og_title":"Pyoderma gangrenosum \u2013 a review - Adacyte","og_description":"Uwe Wollina, Orphanet Journal of Rare Diseases&nbsp;volume&nbsp;2, Article&nbsp;number:&nbsp;19&nbsp;(2007) Pyoderma gangrenosum (PG) is a rare noninfectious neutrophilic dermatosis. Clinically it starts with sterile pustules that rapidly progress and turn into painful ulcers of variable depth and size with undermined violaceous borders. 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