{"id":5634,"date":"2008-07-05T15:03:00","date_gmt":"2008-07-05T15:03:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=5634"},"modified":"2021-07-09T11:18:25","modified_gmt":"2021-07-09T11:18:25","slug":"decreased-numbers-of-foxp3-positive-and-tlr-2-positive-cells-in-intestinal-mucosa-are-associated-with-improvement-in-patients-with-active-inflammatory-bowel-disease-following-selective-leukocyte-apher","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/es\/professional\/scientific-corner\/decreased-numbers-of-foxp3-positive-and-tlr-2-positive-cells-in-intestinal-mucosa-are-associated-with-improvement-in-patients-with-active-inflammatory-bowel-disease-following-selective-leukocyte-apher\/","title":{"rendered":"Decreased numbers of FoxP3-positive and TLR-2-positive cells in intestinal mucosa are associated with improvement in patients with active inflammatory bowel disease following selective leukocyte apheresis"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Muratov+V&amp;cauthor_id=18458843\">Vladislaw Muratov<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18458843\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ulfgren+AK&amp;cauthor_id=18458843\">Ann-Kristin Ulfgren<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Engstr%C3%B6m+M&amp;cauthor_id=18458843\">Marianne Engstr\u00f6m<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Elvin+K&amp;cauthor_id=18458843\">Kerstin Elvin<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Winqvist+O&amp;cauthor_id=18458843\">Ola Winqvist<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=L%C3%B6fberg+R&amp;cauthor_id=18458843\">Robert L\u00f6fberg<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Lundahl+J&amp;cauthor_id=18458843\">Joachim Lundahl<\/a>, J Gastroenterol. 2008;43(4):277-82.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Downregulation of FoxP3 and TLR-2 cells in the colorectal mucosa mirrors both short-and long-term improvement in patients with active IBD responding to GCAP. This observation suggests a potential role of these cells in the pathogenesis of IBD and the induction of immunological tolerance in the mucosa.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18458843\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/18458843\/<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Vladislaw Muratov&nbsp;1,&nbsp;Ann-Kristin Ulfgren,&nbsp;Marianne Engstr\u00f6m,&nbsp;Kerstin Elvin,&nbsp;Ola Winqvist,&nbsp;Robert L\u00f6fberg,&nbsp;Joachim Lundahl, J Gastroenterol. 2008;43(4):277-82. Downregulation of FoxP3 and TLR-2 cells in the colorectal mucosa mirrors both short-and long-term improvement in patients with active IBD responding to GCAP. This observation suggests a potential role of these cells in the pathogenesis of IBD and the induction of immunological tolerance in [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[159,314,388,312,306],"class_list":["post-5634","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-crohns-disease","scientific_tags-digestive","scientific_tags-foxp3-t-cells-tlr-2","scientific_tags-immunology","scientific_tags-ulcerative-colitis"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Decreased numbers of FoxP3-positive and TLR-2-positive cells in intestinal mucosa are associated with improvement in patients with active inflammatory bowel disease following selective leukocyte apheresis - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/decreased-numbers-of-foxp3-positive-and-tlr-2-positive-cells-in-intestinal-mucosa-are-associated-with-improvement-in-patients-with-active-inflammatory-bowel-disease-following-selective-leukocyte-apher\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Decreased numbers of FoxP3-positive and TLR-2-positive cells in intestinal mucosa are associated with improvement in patients with active inflammatory bowel disease following selective leukocyte apheresis - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Vladislaw Muratov&nbsp;1,&nbsp;Ann-Kristin Ulfgren,&nbsp;Marianne Engstr\u00f6m,&nbsp;Kerstin Elvin,&nbsp;Ola Winqvist,&nbsp;Robert L\u00f6fberg,&nbsp;Joachim Lundahl, J Gastroenterol. 2008;43(4):277-82. Downregulation of FoxP3 and TLR-2 cells in the colorectal mucosa mirrors both short-and long-term improvement in patients with active IBD responding to GCAP. This observation suggests a potential role of these cells in the pathogenesis of IBD and the induction of immunological tolerance in [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/decreased-numbers-of-foxp3-positive-and-tlr-2-positive-cells-in-intestinal-mucosa-are-associated-with-improvement-in-patients-with-active-inflammatory-bowel-disease-following-selective-leukocyte-apher\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2021-07-09T11:18:25+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/decreased-numbers-of-foxp3-positive-and-tlr-2-positive-cells-in-intestinal-mucosa-are-associated-with-improvement-in-patients-with-active-inflammatory-bowel-disease-following-selective-leukocyte-apher\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/decreased-numbers-of-foxp3-positive-and-tlr-2-positive-cells-in-intestinal-mucosa-are-associated-with-improvement-in-patients-with-active-inflammatory-bowel-disease-following-selective-leukocyte-apher\/\",\"name\":\"Decreased numbers of FoxP3-positive and TLR-2-positive cells in intestinal mucosa are associated with improvement in patients with active inflammatory bowel disease following selective leukocyte apheresis - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2008-07-05T15:03:00+00:00\",\"dateModified\":\"2021-07-09T11:18:25+00:00\",\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/decreased-numbers-of-foxp3-positive-and-tlr-2-positive-cells-in-intestinal-mucosa-are-associated-with-improvement-in-patients-with-active-inflammatory-bowel-disease-following-selective-leukocyte-apher\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Decreased numbers of FoxP3-positive and TLR-2-positive cells in intestinal mucosa are associated with improvement in patients with active inflammatory bowel disease following selective leukocyte apheresis - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/decreased-numbers-of-foxp3-positive-and-tlr-2-positive-cells-in-intestinal-mucosa-are-associated-with-improvement-in-patients-with-active-inflammatory-bowel-disease-following-selective-leukocyte-apher\/","og_locale":"es_ES","og_type":"article","og_title":"Decreased numbers of FoxP3-positive and TLR-2-positive cells in intestinal mucosa are associated with improvement in patients with active inflammatory bowel disease following selective leukocyte apheresis - Adacyte","og_description":"Vladislaw Muratov&nbsp;1,&nbsp;Ann-Kristin Ulfgren,&nbsp;Marianne Engstr\u00f6m,&nbsp;Kerstin Elvin,&nbsp;Ola Winqvist,&nbsp;Robert L\u00f6fberg,&nbsp;Joachim Lundahl, J Gastroenterol. 2008;43(4):277-82. 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