{"id":3990,"date":"2014-04-19T11:08:00","date_gmt":"2014-04-19T11:08:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=3990"},"modified":"2021-07-12T07:51:24","modified_gmt":"2021-07-12T07:51:24","slug":"therapeutic-effect-of-intensive-granulocyte-and-monocyte-adsorption-apheresis-combined-with-thiopurines-for-steroid-and-biologics-naive-japanese-patients-with-early-diagnosed-crohns-disease","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/es\/professional\/scientific-corner\/therapeutic-effect-of-intensive-granulocyte-and-monocyte-adsorption-apheresis-combined-with-thiopurines-for-steroid-and-biologics-naive-japanese-patients-with-early-diagnosed-crohns-disease\/","title":{"rendered":"Therapeutic effect of intensive granulocyte and monocyte adsorption apheresis combined with thiopurines for steroid- and biologics-naive Japanese patients with early-diagnosed Crohn&#8217;s disease."},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Fukuchi+T&amp;cauthor_id=25015328\">Takumi Fukuchi<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Nakase+H&amp;cauthor_id=25015328\">Hiroshi Nakase<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25015328\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ubukata+S&amp;cauthor_id=25015328\">Satoshi Ubukata<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Matsuura+M&amp;cauthor_id=25015328\">Minoru Matsuura<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yoshino+T&amp;cauthor_id=25015328\">Takuya Yoshino<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Toyonaga+T&amp;cauthor_id=25015328\">Takahiko Toyonaga<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Shimazu+K&amp;cauthor_id=25015328\">Keiji Shimazu<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Koga+H&amp;cauthor_id=25015328\">Hideaki Koga<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yamashita+H&amp;cauthor_id=25015328\">Hiroshi Yamashita<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ito+D&amp;cauthor_id=25015328\">Dai Ito<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ashida+K&amp;cauthor_id=25015328\">Kiyoshi Ashida<\/a>, BMC Gastroenterol. 2014 Jul 11;13:124.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>Combination therapy with intensive GMAA and thiopurines administration rapidly induced high remission in patients with active early-diagnosed CD without serious adverse effect. Mucosal healing was observed in 50.0% of enrolled patients. This combination therapy might be a rational option for patients with early-diagnosed CD.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25015328\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25015328\/<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4105052\/pdf\/1471-230X-14-124.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4105052\/pdf\/1471-230X-14-124.pdf<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Takumi Fukuchi,&nbsp;Hiroshi Nakase&nbsp;1,&nbsp;Satoshi Ubukata,&nbsp;Minoru Matsuura,&nbsp;Takuya Yoshino,&nbsp;Takahiko Toyonaga,&nbsp;Keiji Shimazu,&nbsp;Hideaki Koga,&nbsp;Hiroshi Yamashita,&nbsp;Dai Ito,&nbsp;Kiyoshi Ashida, BMC Gastroenterol. 2014 Jul 11;13:124. Combination therapy with intensive GMAA and thiopurines administration rapidly induced high remission in patients with active early-diagnosed CD without serious adverse effect. Mucosal healing was observed in 50.0% of enrolled patients. This combination therapy might be a rational [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[186,147,187,188,156,185,184],"class_list":["post-3990","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-biologics-naive","scientific_tags-clinical-remission","scientific_tags-early-onset","scientific_tags-japanese-patients","scientific_tags-safety","scientific_tags-steroid-naive","scientific_tags-thiopurines"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Therapeutic effect of intensive granulocyte and monocyte adsorption apheresis combined with thiopurines for steroid- and biologics-naive Japanese patients with early-diagnosed Crohn&#039;s disease. - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/therapeutic-effect-of-intensive-granulocyte-and-monocyte-adsorption-apheresis-combined-with-thiopurines-for-steroid-and-biologics-naive-japanese-patients-with-early-diagnosed-crohns-disease\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Therapeutic effect of intensive granulocyte and monocyte adsorption apheresis combined with thiopurines for steroid- and biologics-naive Japanese patients with early-diagnosed Crohn&#039;s disease. - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Takumi Fukuchi,&nbsp;Hiroshi Nakase&nbsp;1,&nbsp;Satoshi Ubukata,&nbsp;Minoru Matsuura,&nbsp;Takuya Yoshino,&nbsp;Takahiko Toyonaga,&nbsp;Keiji Shimazu,&nbsp;Hideaki Koga,&nbsp;Hiroshi Yamashita,&nbsp;Dai Ito,&nbsp;Kiyoshi Ashida, BMC Gastroenterol. 2014 Jul 11;13:124. Combination therapy with intensive GMAA and thiopurines administration rapidly induced high remission in patients with active early-diagnosed CD without serious adverse effect. Mucosal healing was observed in 50.0% of enrolled patients. 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