{"id":3976,"date":"2015-04-23T09:52:00","date_gmt":"2015-04-23T09:52:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=3976"},"modified":"2021-07-12T07:52:18","modified_gmt":"2021-07-12T07:52:18","slug":"a-case-of-old-age-onset-generalized-pustular-psoriasis-with-a-deficiency-of-il-36rn-ditra-treated-by-granulocyte-and-monocyte-apheresis","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/es\/professional\/scientific-corner\/a-case-of-old-age-onset-generalized-pustular-psoriasis-with-a-deficiency-of-il-36rn-ditra-treated-by-granulocyte-and-monocyte-apheresis\/","title":{"rendered":"A Case of Old Age-Onset Generalized Pustular Psoriasis with a Deficiency of IL-36RN (DITRA) Treated by Granulocyte and Monocyte Apheresis."},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Tominaga+C&amp;cauthor_id=25848350\">Chiharu Tominaga<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25848350\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yamamoto+M&amp;cauthor_id=25848350\">Masaaki Yamamoto<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25848350\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Imai+Y&amp;cauthor_id=25848350\">Yasutomo Imai<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25848350\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yamanishi+K&amp;cauthor_id=25848350\">Kiyofumi Yamanishi<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25848350\/#affiliation-1\">1<\/a><\/sup> , Case Rep Dermatol. 2015 Feb 21;7(1):29-35.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>&nbsp;She is the oldest reported case of GPP with a deficiency of interleukin-36 receptor antagonist (DITRA), although GPP in DITRA has been suggested to usually occur in younger cases with no pre-existing psoriasis vulgaris.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25848350\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25848350\/<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4357681\/pdf\/cde-0007-0029.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4357681\/pdf\/cde-0007-0029.pdf<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Chiharu Tominaga&nbsp;1,&nbsp;Masaaki Yamamoto&nbsp;1,&nbsp;Yasutomo Imai&nbsp;1,&nbsp;Kiyofumi Yamanishi&nbsp;1 , Case Rep Dermatol. 2015 Feb 21;7(1):29-35. &nbsp;She is the oldest reported case of GPP with a deficiency of interleukin-36 receptor antagonist (DITRA), although GPP in DITRA has been suggested to usually occur in younger cases with no pre-existing psoriasis vulgaris. https:\/\/pubmed.ncbi.nlm.nih.gov\/25848350\/ https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4357681\/pdf\/cde-0007-0029.pdf<\/p>\n","protected":false},"template":"","scientific_tags":[276,147,79,151,310,149,312,315,150,67,306],"class_list":["post-3976","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-cases","scientific_tags-clinical-remission","scientific_tags-cytokines","scientific_tags-ditra","scientific_tags-elderly","scientific_tags-il-36rn","scientific_tags-immunology","scientific_tags-others","scientific_tags-psoriasis-vulgaris","scientific_tags-pustular-psoriasis","scientific_tags-ulcerative-colitis"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - 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