{"id":11072,"date":"2024-09-09T13:40:00","date_gmt":"2024-09-09T11:40:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=11072"},"modified":"2025-08-08T13:44:19","modified_gmt":"2025-08-08T11:44:19","slug":"current-pharmacologic-options-and-emerging-therapeutic-approaches-for-the-management-of-ulcerative-colitis-a-narrative-review","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/es\/professional\/scientific-corner\/current-pharmacologic-options-and-emerging-therapeutic-approaches-for-the-management-of-ulcerative-colitis-a-narrative-review\/","title":{"rendered":"Current Pharmacologic Options and Emerging Therapeutic Approaches for the Management of Ulcerative Colitis: A Narrative Review"},"content":{"rendered":"
\n

Sneha Annie Sebastian<\/a>\u00a01<\/a><\/sup>,\u00a0Oroshay Kaiwan<\/a>\u00a02<\/a><\/sup>,\u00a0Edzel L Co<\/a>\u00a03<\/a><\/sup>,\u00a0Meghana Mehendale<\/a>\u00a04<\/a><\/sup>,\u00a0Babu P Mohan<\/a><\/p>\n<\/div>\n\n

\n

Spartan Med Res J.\u00a02024 Sep 9;9(3):123397.\u00a0doi: 10.51894\/001c.123397.\u00a0eCollection 2024.<\/p>\n<\/div>\n\n

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Introduction: <\/strong>Ulcerative colitis (UC) is a chronic inflammatory bowel disorder (IBD) with periods of relapse and remission. Current advancements in clinical research have led to the development of more refined and effective medical therapy for UC.<\/p>\n<\/div>\n\n

\n

Summary of the evidence:\u00a0<\/strong>Traditional therapeutic agents such as 5-aminosalicylates (5-ASAs), sulfasalazine (SASP), corticosteroids, and immunomodulatory drugs have remained the gold standard for decades. However, their novel formulations and dosage regimens have changed their sequences in the medical management of UC. Several other novel drugs are in the final phases of clinical development or have recently received regulatory approval designed to target specific mechanisms involved in the inflammatory cascade for UC.<\/p>\n<\/div>\n\n

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GMA has shown its efficacy in mild to moderate UC and refractory UC (steroid-dependent UC or biologic\/immunologic resistant UC or lost their response to biologics) for remission induction.<\/p>\n<\/div>\n\n

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Conclusions: <\/strong>This narrative review sought to provide a comprehensive knowledge of the potential benefits of standard and emerging therapies, including novel formulations, new chemical entities, and novel therapeutic approaches in managing UC. Keywords: Ulcerative colitis, 5- Aminosalicylic acid, sulfasalazine, corticosteroids, biologics, immunomodulators, novel formulations.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Sneha Annie Sebastian\u00a01,\u00a0Oroshay Kaiwan\u00a02,\u00a0Edzel L Co\u00a03,\u00a0Meghana Mehendale\u00a04,\u00a0Babu P Mohan Spartan Med Res J.\u00a02024 Sep 9;9(3):123397.\u00a0doi: 10.51894\/001c.123397.\u00a0eCollection 2024. Introduction: Ulcerative colitis (UC) is a chronic inflammatory bowel disorder (IBD) with periods of relapse and remission. Current advancements in clinical research have led to the development of more refined and effective medical therapy for UC. Summary of the […]<\/p>\n","protected":false},"template":"","scientific_tags":[721,134,424,326,133,74,435,461,527,603,306],"class_list":["post-11072","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-5-asa","scientific_tags-biologics","scientific_tags-gma","scientific_tags-immunomodulators","scientific_tags-immunosuppressants","scientific_tags-leukocytapheresis","scientific_tags-lor","scientific_tags-refractory","scientific_tags-steroid","scientific_tags-steroid-dependent-2","scientific_tags-ulcerative-colitis"],"acf":[],"yoast_head":"\nCurrent Pharmacologic Options and Emerging Therapeutic Approaches for the Management of Ulcerative Colitis: A Narrative Review - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/current-pharmacologic-options-and-emerging-therapeutic-approaches-for-the-management-of-ulcerative-colitis-a-narrative-review\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Current Pharmacologic Options and Emerging Therapeutic Approaches for the Management of Ulcerative Colitis: A Narrative Review - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Sneha Annie Sebastian\u00a01,\u00a0Oroshay Kaiwan\u00a02,\u00a0Edzel L Co\u00a03,\u00a0Meghana Mehendale\u00a04,\u00a0Babu P Mohan Spartan Med Res J.\u00a02024 Sep 9;9(3):123397.\u00a0doi: 10.51894\/001c.123397.\u00a0eCollection 2024. 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