{"id":11064,"date":"2025-07-18T12:08:00","date_gmt":"2025-07-18T10:08:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=11064"},"modified":"2025-08-08T12:13:03","modified_gmt":"2025-08-08T10:13:03","slug":"management-of-paediatric-ulcerative-colitis-part-1-ambulatory-care-an-updated-evidence-based-consensus-guideline-from-the-european-society-of-paediatric-gastroenterology-hepatology-and-nutr","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/es\/professional\/scientific-corner\/management-of-paediatric-ulcerative-colitis-part-1-ambulatory-care-an-updated-evidence-based-consensus-guideline-from-the-european-society-of-paediatric-gastroenterology-hepatology-and-nutr\/","title":{"rendered":"Management of paediatric ulcerative colitis, part 1: Ambulatory care\u2014An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn’s and Colitis Organisation"},"content":{"rendered":"
\n

Eytan Wine<\/a>,\u00a0Marina Aloi<\/a>,\u00a0Stephanie Van Biervliet<\/a>,\u00a0Jiri Bronsky<\/a>,\u00a0Javier Mart\u00edn di Carpi<\/a>,\u00a0Marco Gasparetto<\/a>,\u00a0Laura Gianolio<\/a>,\u00a0Hannah Gordon<\/a>,\u00a0Iva Hojsak<\/a>,\u00a0Alexandra S. Hudson<\/a>,\u00a0S\u00e9amus Hussey<\/a>,\u00a0Johan van Limbergen<\/a>,\u00a0Erasmo Miele<\/a>,\u00a0Lorenzo Norsa<\/a>,\u00a0Ola Ol\u00e9n<\/a>,\u00a0Gianluca Pellino<\/a>,\u00a0Patrick van Rheenen<\/a>,\u00a0Lissy de Ridder<\/a>,\u00a0Richard K. Russell<\/a>,\u00a0Dror S. Shouval<\/a>,\u00a0Eunice Trindade<\/a>,\u00a0Dan Turner<\/a>,\u00a0David C. Wilson<\/a>,\u00a0Anat Yerushalmy Feler<\/a>,\u00a0Amit Assa<\/a><\/p>\n<\/div>\n\n

\n

J Pediatr Gastroenterol Nutr<\/em>.\u00a02025;\u00a01-51.\u00a0doi:10.1002\/jpn3.70097<\/a><\/p>\n<\/div>\n\n

\n

Objectives<\/h3>\n<\/div>\n\n
\n

Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points.<\/p>\n<\/div>\n\n

\n

Methods<\/h3>\n<\/div>\n\n
\n

These guidelines are an update to those published in 2018 and are a joint effort of the Paediatric IBD Porto group of European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn’s and Colitis Organisation. An extensive literature search with subsequent evidence appraisal using the Oxford methodology was performed, followed by three online voting sessions and a consensus face-to-face meeting. Thirty-nine recommendations and 77 practice points were endorsed by the 25 experts with at least an 84% consensus rate.<\/p>\n<\/div>\n\n

\n

Results<\/h3>\n<\/div>\n\n
\n

Robust evidence-based recommendations and detailed practice points are provided. In addition to reemphasising and updating the role of more \u2018traditional\u2019 UC therapies, these guidelines outline optimising the use of antitumour necrosis factor therapies and integrating newer biologics and small molecules, as well as supportive therapy, to improve outcomes and provide an updated management algorithm. Measurement and monitoring tools and decision aids are provided, and additional aspects, including nutritional support, extraintestinal manifestations, pouchitis, inflammatory bowel disease-unclassified and patient support, are discussed. Some aspects, including surgery and thromboprophylaxis, are covered in the acute severe UC guidelines.<\/p>\n<\/div>\n\n

\n

GMA has a good safety profile, especially in difficult-to-treat and paediatric settings.<\/a><\/sup>\u00a0GMA also requires central venous access but may still be considered in children with UC who do not respond or lose response to conventional treatments, but more studies are needed before formal recommendations can be made.<\/p>\n<\/div>\n\n

\n

Conclusions<\/h3>\n<\/div>\n\n
\n

These guidelines serve as an aid in managing children with UC through a combination of evidence-based recommendations and more practical practice points in the ambulatory setting.<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Eytan Wine,\u00a0Marina Aloi,\u00a0Stephanie Van Biervliet,\u00a0Jiri Bronsky,\u00a0Javier Mart\u00edn di Carpi,\u00a0Marco Gasparetto,\u00a0Laura Gianolio,\u00a0Hannah Gordon,\u00a0Iva Hojsak,\u00a0Alexandra S. Hudson,\u00a0S\u00e9amus Hussey,\u00a0Johan van Limbergen,\u00a0Erasmo Miele,\u00a0Lorenzo Norsa,\u00a0Ola Ol\u00e9n,\u00a0Gianluca Pellino,\u00a0Patrick van Rheenen,\u00a0Lissy de Ridder,\u00a0Richard K. Russell,\u00a0Dror S. Shouval,\u00a0Eunice Trindade,\u00a0Dan Turner,\u00a0David C. Wilson,\u00a0Anat Yerushalmy Feler,\u00a0Amit Assa J Pediatr Gastroenterol Nutr.\u00a02025;\u00a01-51.\u00a0doi:10.1002\/jpn3.70097 Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain […]<\/p>\n","protected":false},"template":"","scientific_tags":[424,350,435,405,461,156,306],"class_list":["post-11064","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-gma","scientific_tags-guidelines","scientific_tags-lor","scientific_tags-pediatric","scientific_tags-refractory","scientific_tags-safety","scientific_tags-ulcerative-colitis"],"acf":[],"yoast_head":"\nManagement of paediatric ulcerative colitis, part 1: Ambulatory care\u2014An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/management-of-paediatric-ulcerative-colitis-part-1-ambulatory-care-an-updated-evidence-based-consensus-guideline-from-the-european-society-of-paediatric-gastroenterology-hepatology-and-nutr\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Management of paediatric ulcerative colitis, part 1: Ambulatory care\u2014An updated evidence-based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Eytan Wine,\u00a0Marina Aloi,\u00a0Stephanie Van Biervliet,\u00a0Jiri Bronsky,\u00a0Javier Mart\u00edn di Carpi,\u00a0Marco Gasparetto,\u00a0Laura Gianolio,\u00a0Hannah Gordon,\u00a0Iva Hojsak,\u00a0Alexandra S. 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