{"id":9060,"date":"2023-10-03T12:16:00","date_gmt":"2023-10-03T10:16:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=9060"},"modified":"2024-04-30T13:52:04","modified_gmt":"2024-04-30T11:52:04","slug":"adsorptive-cytapheresis-in-ulcerative-colitis-a-non-pharmacological-therapeutic-approach-revisited","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/adsorptive-cytapheresis-in-ulcerative-colitis-a-non-pharmacological-therapeutic-approach-revisited\/","title":{"rendered":"Adsorptive cytapheresis in ulcerative colitis: A non-pharmacological therapeutic approach revisited"},"content":{"rendered":"
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Filippo Vernia<\/a>\u00a01<\/a><\/sup>,\u00a0Angelo Viscido<\/a>\u00a01<\/a><\/sup>,\u00a0Giovanni Latella<\/a>\u00a01<\/a><\/sup>J Clin Apher.\u00a02023 Dec;38(6):746-754<\/p>\n<\/div>\n\n

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Adsorptive cytapheresis proves effective in a proportion of patients affected by ulcerative colitis. Relatively high cost and the need for apheresis facilities, prevented the widespread use of this therapeutic approach. More so following the introduction of anti-TNF\u03b1 biosimilars which proved both effective and inexpensive. Anti-TNF\u03b1 agents, however, are burdened by high rate of primary and secondary non-response and prompt switching to new, high-cost biologics, and small molecules. The present review analyzes advantages and disadvantages of adsorptive cytapheresis in the present clinical scenario and suggests its repositioning in the therapeutic workup of selected subgroups of ulcerative colitis patients. The extremely favorable safety profile makes adsorptive cytapheresis a viable therapeutic option in elderly and high-risk UC patients, as well as potential second-line treatment in corticosteroid-dependent patients and poor responders to first-line biologics.<\/p>\n<\/div>\n\n

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Adsorptive cytapheresis in ulcerative colitis: A non-pharmacological therapeutic approach revisited – PubMed (nih.gov)<\/a><\/p>\n<\/div>\n\n

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Adsorptive cytapheresis in ulcerative colitis: A non\u2010pharmacological therapeutic approach revisited – Vernia – 2023 – Journal of Clinical Apheresis – Wiley Online Library<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Filippo Vernia\u00a01,\u00a0Angelo Viscido\u00a01,\u00a0Giovanni Latella\u00a01J Clin Apher.\u00a02023 Dec;38(6):746-754 Adsorptive cytapheresis proves effective in a proportion of patients affected by ulcerative colitis. Relatively high cost and the need for apheresis facilities, prevented the widespread use of this therapeutic approach. More so following the introduction of anti-TNF\u03b1 biosimilars which proved both effective and inexpensive. Anti-TNF\u03b1 agents, however, are […]<\/p>\n","protected":false},"template":"","scientific_tags":[310,424,780,434,505,779,156,603,306],"class_list":["post-9060","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-elderly","scientific_tags-gma","scientific_tags-high-risk-patients","scientific_tags-loss-of-response","scientific_tags-partial-response","scientific_tags-positionning","scientific_tags-safety","scientific_tags-steroid-dependent-2","scientific_tags-ulcerative-colitis"],"acf":{"sc_authors":"https:\/\/pubmed.ncbi.nlm.nih.gov\/37787399\/<\/a>\r\n\r\nhttps:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jca.22091<\/a>"},"yoast_head":"\nAdsorptive cytapheresis in ulcerative colitis: A non-pharmacological therapeutic approach revisited - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/adsorptive-cytapheresis-in-ulcerative-colitis-a-non-pharmacological-therapeutic-approach-revisited\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Adsorptive cytapheresis in ulcerative colitis: A non-pharmacological therapeutic approach revisited - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Filippo Vernia\u00a01,\u00a0Angelo Viscido\u00a01,\u00a0Giovanni Latella\u00a01J Clin Apher.\u00a02023 Dec;38(6):746-754 Adsorptive cytapheresis proves effective in a proportion of patients affected by ulcerative colitis. Relatively high cost and the need for apheresis facilities, prevented the widespread use of this therapeutic approach. More so following the introduction of anti-TNF\u03b1 biosimilars which proved both effective and inexpensive. 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