{"id":8513,"date":"2022-10-06T14:27:00","date_gmt":"2022-10-06T14:27:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=8513"},"modified":"2024-04-30T14:19:31","modified_gmt":"2024-04-30T12:19:31","slug":"granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/","title":{"rendered":"Granulocyte Apheresis: Can It Be Associated with Anti PD-1 Therapy for Melanoma?"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/sciprofiles.com\/profile\/author\/M3RsU1pPdFpRWjI0UUEwb1dsSHJRcVZaYk94TndZbFhaUWhqRTJ3eGJ3bz0=\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Alvise Sernicola<\/strong><\/a><sup>\u00a01<\/sup><a href=\"https:\/\/orcid.org\/0000-0002-1985-0326\" target=\"_blank\" rel=\"noreferrer noopener\"><\/a>,<a href=\"https:\/\/sciprofiles.com\/profile\/author\/VWhCK3ZFSmIrYTZ1ak0vcmdYdktDWUZHY2hYcjQyTWk0ZXNNSnpVZ3g3Yz0=\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Anna Colpo<\/strong><\/a><sup>\u00a02<\/sup>,<a href=\"https:\/\/sciprofiles.com\/profile\/author\/S00yM0JxeVVEODFtaktGa0dMcEpSTmRWWkJWbTFUSEdTY2dqSVFlb0M0RT0=\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Anca Irina Leahu<\/strong><\/a><sup>\u00a02<\/sup>\u00a0and <a href=\"https:\/\/sciprofiles.com\/profile\/24658\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Mauro Alaibac<\/strong><\/a><sup>\u00a01<\/sup><em>Medicina<\/em>\u00a0<strong>2022<\/strong>,\u00a0<em>58<\/em>(10), 1398;\u00a0<a href=\"https:\/\/doi.org\/10.3390\/medicina58101398\">https:\/\/doi.org\/10.3390\/medicina58101398<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>In the field of advanced melanoma, there is an urgent need to investigate novel approaches targeting specific components of the cancer\u2013immunity cycle beyond immune checkpoint inhibitors. The authors reviewed the basic understanding of the role of neutrophils in cancer biology, and the latest clinical evidence supporting the correlation between cancer-associated neutrophils and the prognosis and response to the immunotherapy of advanced melanoma. Finally, they propose that granulocyte and monocyte apheresis, an emerging non-pharmacological treatment in current dermatology, could become an investigative treatment targeting melanoma-associated neutrophils which could be potentially used in combination with the usual immune checkpoint inhibitors.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/www.mdpi.com\/1648-9144\/58\/10\/1398\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.mdpi.com\/1648-9144\/58\/10\/1398<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Alvise Sernicola\u00a01,Anna Colpo\u00a02,Anca Irina Leahu\u00a02\u00a0and Mauro Alaibac\u00a01Medicina\u00a02022,\u00a058(10), 1398;\u00a0https:\/\/doi.org\/10.3390\/medicina58101398 In the field of advanced melanoma, there is an urgent need to investigate novel approaches targeting specific components of the cancer\u2013immunity cycle beyond immune checkpoint inhibitors. The authors reviewed the basic understanding of the role of neutrophils in cancer biology, and the latest clinical evidence supporting the [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[690,303,424,691,689,692,460,693],"class_list":["post-8513","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-anti-pd-1","scientific_tags-combination","scientific_tags-gma","scientific_tags-immune-checkpoint-inhibitors","scientific_tags-melanoma","scientific_tags-neutrophils","scientific_tags-prognosis","scientific_tags-response"],"acf":{"sc_authors":"<a href=\"https:\/\/www.mdpi.com\/1648-9144\/58\/10\/1398\">https:\/\/www.mdpi.com\/1648-9144\/58\/10\/1398<\/a>"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Granulocyte Apheresis: Can It Be Associated with Anti PD-1 Therapy for Melanoma? - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Granulocyte Apheresis: Can It Be Associated with Anti PD-1 Therapy for Melanoma? - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Alvise Sernicola\u00a01,Anna Colpo\u00a02,Anca Irina Leahu\u00a02\u00a0and Mauro Alaibac\u00a01Medicina\u00a02022,\u00a058(10), 1398;\u00a0https:\/\/doi.org\/10.3390\/medicina58101398 In the field of advanced melanoma, there is an urgent need to investigate novel approaches targeting specific components of the cancer\u2013immunity cycle beyond immune checkpoint inhibitors. The authors reviewed the basic understanding of the role of neutrophils in cancer biology, and the latest clinical evidence supporting the [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2024-04-30T12:19:31+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data1\" content=\"1\u00a0Minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/\",\"name\":\"Granulocyte Apheresis: Can It Be Associated with Anti PD-1 Therapy for Melanoma? - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"2022-10-06T14:27:00+00:00\",\"dateModified\":\"2024-04-30T12:19:31+00:00\",\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"de\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Granulocyte Apheresis: Can It Be Associated with Anti PD-1 Therapy for Melanoma? - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/","og_locale":"de_DE","og_type":"article","og_title":"Granulocyte Apheresis: Can It Be Associated with Anti PD-1 Therapy for Melanoma? - Adacyte","og_description":"Alvise Sernicola\u00a01,Anna Colpo\u00a02,Anca Irina Leahu\u00a02\u00a0and Mauro Alaibac\u00a01Medicina\u00a02022,\u00a058(10), 1398;\u00a0https:\/\/doi.org\/10.3390\/medicina58101398 In the field of advanced melanoma, there is an urgent need to investigate novel approaches targeting specific components of the cancer\u2013immunity cycle beyond immune checkpoint inhibitors. The authors reviewed the basic understanding of the role of neutrophils in cancer biology, and the latest clinical evidence supporting the [&hellip;]","og_url":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/","og_site_name":"Adacyte","article_modified_time":"2024-04-30T12:19:31+00:00","twitter_card":"summary_large_image","twitter_misc":{"Gesch\u00e4tzte Lesezeit":"1\u00a0Minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/","url":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/","name":"Granulocyte Apheresis: Can It Be Associated with Anti PD-1 Therapy for Melanoma? - Adacyte","isPartOf":{"@id":"https:\/\/www.adacyte.com\/#website"},"datePublished":"2022-10-06T14:27:00+00:00","dateModified":"2024-04-30T12:19:31+00:00","inLanguage":"de","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-apheresis-can-it-be-associated-with-anti-pd-1-therapy-for-melanoma\/"]}]},{"@type":"WebSite","@id":"https:\/\/www.adacyte.com\/#website","url":"https:\/\/www.adacyte.com\/","name":"Adacyte","description":"Adacyte Therapeutics","publisher":{"@id":"https:\/\/www.adacyte.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.adacyte.com\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"de"},{"@type":"Organization","@id":"https:\/\/www.adacyte.com\/#organization","name":"Adacyte","url":"https:\/\/www.adacyte.com\/","logo":{"@type":"ImageObject","inLanguage":"de","@id":"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/","url":"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg","contentUrl":"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg","width":165,"height":46,"caption":"Adacyte"},"image":{"@id":"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.adacyte.com\/de\/wp-json\/wp\/v2\/scientific-corner\/8513","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.adacyte.com\/de\/wp-json\/wp\/v2\/scientific-corner"}],"about":[{"href":"https:\/\/www.adacyte.com\/de\/wp-json\/wp\/v2\/types\/scientific-corner"}],"wp:attachment":[{"href":"https:\/\/www.adacyte.com\/de\/wp-json\/wp\/v2\/media?parent=8513"}],"wp:term":[{"taxonomy":"scientific_tags","embeddable":true,"href":"https:\/\/www.adacyte.com\/de\/wp-json\/wp\/v2\/scientific_tags?post=8513"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}