{"id":8508,"date":"2006-06-06T10:12:00","date_gmt":"2006-06-06T10:12:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=8508"},"modified":"2022-10-26T10:16:22","modified_gmt":"2022-10-26T10:16:22","slug":"granulocyte-and-monocyte-adsorption-apheresis-for-cutaneous-allergic-vasculitis","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/granulocyte-and-monocyte-adsorption-apheresis-for-cutaneous-allergic-vasculitis\/","title":{"rendered":"Granulocyte and monocyte adsorption apheresis for cutaneous allergic vasculitis"},"content":{"rendered":"
\n

Takuro Kanekura<\/a>\u00a01<\/a><\/sup>,\u00a0Noriko Yoshii<\/a>,\u00a0Koichi Kawahara<\/a>,\u00a0Ikuro Maruyama<\/a>,\u00a0Tamotsu Kanzaki<\/a><\/p>\n<\/div>\n\n

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Ther Apher Dial<\/a>\u00a02006 Jun;10(3):287-90.\u00a0doi: 10.1111\/j.1744-9987.2006.00335.x.<\/p>\n<\/div>\n\n

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Cutaneous allergic vasculitis (CAV) is characterized clinically by purpuric patches with secondary ulcerations, and histologically by leukocytoclastic vasculitis with neutrophil infiltrates. Granulocyte and monocyte adsorption apheresis (GCAP) is an extracorporeal apheresis instrument using a column containing cellulose acetate beads designed to remove pathogenic granulocytes. Here we report our assessment of the efficacy of GCAP for recurrent leg ulcers in a 49-year-old woman with CAV. She underwent five GCAP treatments at one-week intervals. In each treatment session, 1800 mL of blood was processed. Her leg ulcers responded well and her white blood cell and neutrophil counts and the expression level of CD11b\/CD18, a marker for activated neutrophils, on her peripheral neutrophils were reduced from 7500\/microL to 6500\/microL, 4350\/microL to 3315\/microL, and 64.9 MFI (mean fluorescence intensity) to 27.0 MFI (normal controls: 10.5 +\/- 1.2 MFI) by GCAP, respectively. These results suggest that GCAP is useful for skin disorders with leucocytoclastic vasculitis.<\/p>\n<\/div>\n\n

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https:\/\/pubmed.ncbi.nlm.nih.gov\/16817796\/<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Takuro Kanekura\u00a01,\u00a0Noriko Yoshii,\u00a0Koichi Kawahara,\u00a0Ikuro Maruyama,\u00a0Tamotsu Kanzaki Ther Apher Dial\u00a02006 Jun;10(3):287-90.\u00a0doi: 10.1111\/j.1744-9987.2006.00335.x. Cutaneous allergic vasculitis (CAV) is characterized clinically by purpuric patches with secondary ulcerations, and histologically by leukocytoclastic vasculitis with neutrophil infiltrates. Granulocyte and monocyte adsorption apheresis (GCAP) is an extracorporeal apheresis instrument using a column containing cellulose acetate beads designed to remove pathogenic granulocytes. […]<\/p>\n","protected":false},"template":"","scientific_tags":[608,680,638,198,664,446,157,672,424,681,366,662],"class_list":["post-8508","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-activated-neutrophils","scientific_tags-cav","scientific_tags-cd11b","scientific_tags-cd18","scientific_tags-cutaneous-allergic-vasculitis","scientific_tags-effectiveness","scientific_tags-efficacy","scientific_tags-gcap","scientific_tags-gma","scientific_tags-leucocytoclastic-vasculitis","scientific_tags-neutrophil-infiltration","scientific_tags-skin-disorders"],"acf":{"sc_authors":""},"yoast_head":"\nGranulocyte and monocyte adsorption apheresis for cutaneous allergic vasculitis - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/granulocyte-and-monocyte-adsorption-apheresis-for-cutaneous-allergic-vasculitis\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Granulocyte and monocyte adsorption apheresis for cutaneous allergic vasculitis - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Takuro Kanekura\u00a01,\u00a0Noriko Yoshii,\u00a0Koichi Kawahara,\u00a0Ikuro Maruyama,\u00a0Tamotsu Kanzaki Ther Apher Dial\u00a02006 Jun;10(3):287-90.\u00a0doi: 10.1111\/j.1744-9987.2006.00335.x. Cutaneous allergic vasculitis (CAV) is characterized clinically by purpuric patches with secondary ulcerations, and histologically by leukocytoclastic vasculitis with neutrophil infiltrates. Granulocyte and monocyte adsorption apheresis (GCAP) is an extracorporeal apheresis instrument using a column containing cellulose acetate beads designed to remove pathogenic granulocytes. 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Cutaneous allergic vasculitis (CAV) is characterized clinically by purpuric patches with secondary ulcerations, and histologically by leukocytoclastic vasculitis with neutrophil infiltrates. Granulocyte and monocyte adsorption apheresis (GCAP) is an extracorporeal apheresis instrument using a column containing cellulose acetate beads designed to remove pathogenic granulocytes. 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