{"id":6580,"date":"2019-10-18T16:26:00","date_gmt":"2019-10-18T16:26:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=6580"},"modified":"2024-05-02T10:51:03","modified_gmt":"2024-05-02T08:51:03","slug":"gs2-03-japanese-apheresis-guidelines-for-the-management-and-treatment-of-generalized-pustular-psoriasis-pustulosis-palmoplantaris-and-psoriasis-arthropathica","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/gs2-03-japanese-apheresis-guidelines-for-the-management-and-treatment-of-generalized-pustular-psoriasis-pustulosis-palmoplantaris-and-psoriasis-arthropathica\/","title":{"rendered":"GS2-03 Japanese apheresis guidelines for the management and treatment of generalized pustular psoriasis, pustulosis palmoplantaris and psoriasis arthropathica"},"content":{"rendered":"
\n

Miho Hatanaka, Yuko Higashi, Takuro Kanekura<\/p>\n<\/div>\n\n

\n

poster at ISFA 2019 pag 104<\/p>\n<\/div>\n\n

\n

Generalized pustular psoriasis (GPP) is a rare disease characterized by recurrent fever and
systemic flushing accompanied by extensive sterile pustules. Treatments of GPP are usually
topical corticosteroids, activated vitamin D3 ointment, ultraviolet light (UV) therapy, and
oral administration of etretinate, cyclosporine, or methotrexate. Recently, biologics such as
TNF- \u03b1; inhibitors, anti-IL-17- and anti-IL-23 antibodies are used. Pustulosis palmoplantaris
(PPP) is a chronic recurrent disorder of the palms and soles characterized by sterile intradermal
pustules. PPP often accompanies joint symptoms. In some instances, PPP is associated with
a focus of infection somewhere in the body; elimination of the infection sometimes improve
symptom. Some treatments of GPP are used for PPP. Psoriatic arthritis (PsA) is a disease
characterized by skin and nail psoriasis together with widespread musculoskeletal inflammation
such as peripheral joint disease, axial joint disease, enthesitis, and dactylitis. Treatment of
PsA is oral administration of NSAID\u2019s, cyclosporine, methotrexate and phosphodiesterase 4
inhibitors for mild to moderate cases. Biologics; TNF- \u03b1inhibitors, anti-IL-17- and anti-IL-23
antibodies; have been approved for severe or advanced cases. Granulocyte\/monocyte adsorption
apheresis (GMA) is an extracorporeal therapy designed to remove and suppress the functions
of neutrophils, macrophages and monocytes that accumulate in the inflamed tissue and are
involved in the pahogenesis. GMA may be considered as a safe treatment modality with few
side-effects for GPP, PPP and PsA. The effect and safety of GMA have been reported mostly in
case reports. Although the effect and safety of GMA were demonstrated in a multicenter study.
GMA\u2019s utility is expected based on the mechanism of action.<\/p>\n<\/div>\n\n

\n

http:\/\/www.atalacia.com\/isfa\/data\/abstract.pdf<\/a><\/p>\n<\/div>\n\n

\n

<\/p>\n<\/div>\n\n

\n

<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Miho Hatanaka, Yuko Higashi, Takuro Kanekura poster at ISFA 2019 pag 104 Generalized pustular psoriasis (GPP) is a rare disease characterized by recurrent fever andsystemic flushing accompanied by extensive sterile pustules. Treatments of GPP are usuallytopical corticosteroids, activated vitamin D3 ointment, ultraviolet light (UV) therapy, andoral administration of etretinate, cyclosporine, or methotrexate. Recently, biologics such […]<\/p>\n","protected":false},"template":"","scientific_tags":[276,157,475,348,100,68,80,67,53,156,271],"class_list":["post-6580","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-cases","scientific_tags-efficacy","scientific_tags-extracorporeal-circulation","scientific_tags-generalized-pustular-psoriasis","scientific_tags-multicenter","scientific_tags-palmoplantar-pustulosis","scientific_tags-psoriatic-arthritis","scientific_tags-pustular-psoriasis","scientific_tags-refractory-patients","scientific_tags-safety","scientific_tags-study"],"acf":{"sc_authors":"https:\/\/www.atalacia.com\/isfa\/data\/abstract.pdf<\/a>"},"yoast_head":"\nGS2-03 Japanese apheresis guidelines for the management and treatment of generalized pustular psoriasis, pustulosis palmoplantaris and psoriasis arthropathica - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/gs2-03-japanese-apheresis-guidelines-for-the-management-and-treatment-of-generalized-pustular-psoriasis-pustulosis-palmoplantaris-and-psoriasis-arthropathica\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"GS2-03 Japanese apheresis guidelines for the management and treatment of generalized pustular psoriasis, pustulosis palmoplantaris and psoriasis arthropathica - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Miho Hatanaka, Yuko Higashi, Takuro Kanekura poster at ISFA 2019 pag 104 Generalized pustular psoriasis (GPP) is a rare disease characterized by recurrent fever andsystemic flushing accompanied by extensive sterile pustules. 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