{"id":6435,"date":"2021-10-28T09:17:35","date_gmt":"2021-10-28T09:17:35","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=6435"},"modified":"2024-05-02T09:39:21","modified_gmt":"2024-05-02T07:39:21","slug":"the-new-molecules-are-changing-the-course-of-pediatric-chronically-active-ulcerative-colitis-a-series-of-pediatric-cases","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/the-new-molecules-are-changing-the-course-of-pediatric-chronically-active-ulcerative-colitis-a-series-of-pediatric-cases\/","title":{"rendered":"The New Molecules Are Changing the Course of Pediatric Chronically Active Ulcerative Colitis: A Series of Pediatric Cases"},"content":{"rendered":"
\n

Rafael Mart\u00edn-Masot, MD, *Pilar Ortiz P\u00e9rez, MD, *Encarnaci\u00f3n Torcuato Rubio, MD,
*Javier Blasco Alonso, PhD, *Marta Herrador L\u00f3pez, \u2020Carmen Gallego Fern\u00e1ndez, PhD,
and *V\u00edctor Manuel Navas-L\u00f3pez, PhD, DOI: 10.1097\/PG9.0000000000000100<\/p>\n<\/div>\n\n

\n

Chronically active ulcerative colitis (UC) constitutes a challenge in an era where medical therapeutic options have increased while experience with colectomies has decreased. The change in the therapeutic paradigm of the disease means that patients with chronically active UC are being managed waiting to find their therapeutic target. We present 2 cases of children with chronically active UC who did not respond to intravenous steroids nor sequential therapy. A response was obtained with ustekinumab and tofacitinib, 2 drugs widely used in adults but still with little evidence in children. Highlighting the important role of patients and their families helped decision making, facilitating the work of the medical team. With multidisciplinary
management and close follow-up, they have been able to avoid surgery enter\u0002ing complete clinical remission.<\/p>\n<\/div>\n\n

\n

https:\/\/journals.lww.com\/jpgnr\/fulltext\/2021\/08000\/the_new_molecules_are_changing_the_course_of.25.aspx<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Rafael Mart\u00edn-Masot, MD, *Pilar Ortiz P\u00e9rez, MD, *Encarnaci\u00f3n Torcuato Rubio, MD,*Javier Blasco Alonso, PhD, *Marta Herrador L\u00f3pez, \u2020Carmen Gallego Fern\u00e1ndez, PhD,and *V\u00edctor Manuel Navas-L\u00f3pez, PhD, DOI: 10.1097\/PG9.0000000000000100 Chronically active ulcerative colitis (UC) constitutes a challenge in an era where medical therapeutic options have increased while experience with colectomies has decreased. The change in the therapeutic […]<\/p>\n","protected":false},"template":"","scientific_tags":[276,430,426,313,306],"class_list":["post-6435","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-cases","scientific_tags-colectomy","scientific_tags-ibd","scientific_tags-pediatry","scientific_tags-ulcerative-colitis"],"acf":{"sc_authors":"https:\/\/journals.lww.com\/jpgnr\/fulltext\/<\/a>"},"yoast_head":"\nThe New Molecules Are Changing the Course of Pediatric Chronically Active Ulcerative Colitis: A Series of Pediatric Cases - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/the-new-molecules-are-changing-the-course-of-pediatric-chronically-active-ulcerative-colitis-a-series-of-pediatric-cases\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The New Molecules Are Changing the Course of Pediatric Chronically Active Ulcerative Colitis: A Series of Pediatric Cases - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Rafael Mart\u00edn-Masot, MD, *Pilar Ortiz P\u00e9rez, MD, *Encarnaci\u00f3n Torcuato Rubio, MD,*Javier Blasco Alonso, PhD, *Marta Herrador L\u00f3pez, \u2020Carmen Gallego Fern\u00e1ndez, PhD,and *V\u00edctor Manuel Navas-L\u00f3pez, PhD, DOI: 10.1097\/PG9.0000000000000100 Chronically active ulcerative colitis (UC) constitutes a challenge in an era where medical therapeutic options have increased while experience with colectomies has decreased. 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