{"id":5713,"date":"1996-07-06T11:14:00","date_gmt":"1996-07-06T11:14:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=5713"},"modified":"2022-04-20T11:28:20","modified_gmt":"2022-04-20T11:28:20","slug":"extracorporeal-granulocytapheresis-for-cancer-and-rheumatoid-arthritis","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/extracorporeal-granulocytapheresis-for-cancer-and-rheumatoid-arthritis\/","title":{"rendered":"Extracorporeal granulocytapheresis for cancer and rheumatoid arthritis"},"content":{"rendered":"
\n

Motoki Yonekawa \u2217<\/sup>Akio Kawamura\u2217<\/sup>Takashi Komai\u2020<\/sup>Tetsuzo Agishi\u2021<\/sup>Masakazu Adachi\u00a7<\/sup><\/a> , https:\/\/doi.org\/10.1016\/0955-3886(96)00030-6<\/a><\/p>\n<\/div>\n\n

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In cancer and rheumatoid arthritis, granulocytosis is often observed and indicates the progress of disease. We developed a granulocytapheresis system to permit granulocyte reduction. Cellulose acetate was found to be a selective and effective adsorbent. In an in vivo<\/em> study using an acetate bead column, 9.2 \u00d7 108<\/sup> leukocytes were collected. Initially, granulocytapheresis was applied to terminal patients or those with stage IV cancer. Pain, cough and bloody sputum were reduced in spite of no decrease in the tumor size. Granulocytapheresis appears to prevent inflammatory damage in or around the tumor site. This granulocyte reduction technique was also applied to patients with rheumatoid arthritis. The Lansbury index markedly improved after treatment. As cytokines and adhesion molecules might contribute to symptoms, granulocytapheresis may be useful in improving the \u201cQuality of Life\u201d in these diseases.<\/p>\n<\/div>\n\n

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https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/0955388696000306<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Motoki Yonekawa \u2217Akio Kawamura\u2217Takashi Komai\u2020Tetsuzo Agishi\u2021Masakazu Adachi\u00a7 , https:\/\/doi.org\/10.1016\/0955-3886(96)00030-6 In cancer and rheumatoid arthritis, granulocytosis is often observed and indicates the progress of disease. We developed a granulocytapheresis system to permit granulocyte reduction. Cellulose acetate was found to be a selective and effective adsorbent. In an in vivo study using an acetate bead column, 9.2 \u00d7 108 leukocytes […]<\/p>\n","protected":false},"template":"","scientific_tags":[318,336],"class_list":["post-5713","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-oncology","scientific_tags-rheumatology"],"acf":[],"yoast_head":"\nExtracorporeal granulocytapheresis for cancer and rheumatoid arthritis - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/extracorporeal-granulocytapheresis-for-cancer-and-rheumatoid-arthritis\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Extracorporeal granulocytapheresis for cancer and rheumatoid arthritis - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Motoki Yonekawa \u2217Akio Kawamura\u2217Takashi Komai\u2020Tetsuzo Agishi\u2021Masakazu Adachi\u00a7 , https:\/\/doi.org\/10.1016\/0955-3886(96)00030-6 In cancer and rheumatoid arthritis, granulocytosis is often observed and indicates the progress of disease. We developed a granulocytapheresis system to permit granulocyte reduction. Cellulose acetate was found to be a selective and effective adsorbent. In an in vivo study using an acetate bead column, 9.2 \u00d7 108 leukocytes […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/extracorporeal-granulocytapheresis-for-cancer-and-rheumatoid-arthritis\/\" \/>\n<meta property=\"og:site_name\" content=\"Adacyte\" \/>\n<meta property=\"article:modified_time\" content=\"2022-04-20T11:28:20+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Gesch\u00e4tzte Lesezeit\" \/>\n\t<meta name=\"twitter:data1\" content=\"1\u00a0Minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/extracorporeal-granulocytapheresis-for-cancer-and-rheumatoid-arthritis\/\",\"url\":\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/extracorporeal-granulocytapheresis-for-cancer-and-rheumatoid-arthritis\/\",\"name\":\"Extracorporeal granulocytapheresis for cancer and rheumatoid arthritis - Adacyte\",\"isPartOf\":{\"@id\":\"https:\/\/www.adacyte.com\/#website\"},\"datePublished\":\"1996-07-06T11:14:00+00:00\",\"dateModified\":\"2022-04-20T11:28:20+00:00\",\"inLanguage\":\"de\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/extracorporeal-granulocytapheresis-for-cancer-and-rheumatoid-arthritis\/\"]}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.adacyte.com\/#website\",\"url\":\"https:\/\/www.adacyte.com\/\",\"name\":\"Adacyte\",\"description\":\"Adacyte Therapeutics\",\"publisher\":{\"@id\":\"https:\/\/www.adacyte.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.adacyte.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"de\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.adacyte.com\/#organization\",\"name\":\"Adacyte\",\"url\":\"https:\/\/www.adacyte.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"de\",\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"contentUrl\":\"https:\/\/www.adacyte.com\/wp-content\/uploads\/2021\/01\/logo-adacyte.svg\",\"width\":165,\"height\":46,\"caption\":\"Adacyte\"},\"image\":{\"@id\":\"https:\/\/www.adacyte.com\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Extracorporeal granulocytapheresis for cancer and rheumatoid arthritis - Adacyte","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.adacyte.com\/professional\/scientific-corner\/extracorporeal-granulocytapheresis-for-cancer-and-rheumatoid-arthritis\/","og_locale":"de_DE","og_type":"article","og_title":"Extracorporeal granulocytapheresis for cancer and rheumatoid arthritis - Adacyte","og_description":"Motoki Yonekawa \u2217Akio Kawamura\u2217Takashi Komai\u2020Tetsuzo Agishi\u2021Masakazu Adachi\u00a7 , https:\/\/doi.org\/10.1016\/0955-3886(96)00030-6 In cancer and rheumatoid arthritis, granulocytosis is often observed and indicates the progress of disease. 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