{"id":5620,"date":"2009-07-05T14:21:00","date_gmt":"2009-07-05T14:21:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=5620"},"modified":"2021-07-09T11:18:42","modified_gmt":"2021-07-09T11:18:42","slug":"leukocytapheresis-in-ulcerative-colitis-a-possible-alternative-to-biological-therapy","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/leukocytapheresis-in-ulcerative-colitis-a-possible-alternative-to-biological-therapy\/","title":{"rendered":"Leukocytapheresis in ulcerative colitis: a possible alternative to biological therapy?"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Arseneau+KO&amp;cauthor_id=19540820\">K O Arseneau<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19540820\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Cominelli+F&amp;cauthor_id=19540820\">F Cominelli<\/a>, Dig Liver Dis. 2009 Aug;41(8):551-2.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>In summary, selective adsorption of granulocytes and monocytes from the peripheral blood<br>of patients with active ulcerative colitis using the extracorporal Adacolumn GMA appears to<br>be an extremely safe treatment modality. Although conflicting results have been reported<br>regarding the efficacy of Adacolumn GMA, this study by Hibi et al. adds to the existing<br>literature by providing data from the largest population of ulcerative colitis patients yet to be<br>studied. If the observed treatment effect of 77.7% is representative of the true response rate,<br>Adacolumn GMA would be a safe alternative to biological therapies for patients with<br>refractory ulcerative colitis. In addition, granulocyte fractions could be used to help identify<br>patients who are most likely to benefit from this procedure<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19540820\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/19540820\/<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3572230\/pdf\/nihms125646.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3572230\/pdf\/nihms125646.pdf<\/a><\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>K O Arseneau&nbsp;1,&nbsp;F Cominelli, Dig Liver Dis. 2009 Aug;41(8):551-2. In summary, selective adsorption of granulocytes and monocytes from the peripheral bloodof patients with active ulcerative colitis using the extracorporal Adacolumn GMA appears tobe an extremely safe treatment modality. Although conflicting results have been reportedregarding the efficacy of Adacolumn GMA, this study by Hibi et al. [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[314,306],"class_list":["post-5620","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-digestive","scientific_tags-ulcerative-colitis"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Leukocytapheresis in ulcerative colitis: a possible alternative to biological therapy? - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/leukocytapheresis-in-ulcerative-colitis-a-possible-alternative-to-biological-therapy\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Leukocytapheresis in ulcerative colitis: a possible alternative to biological therapy? - Adacyte\" \/>\n<meta property=\"og:description\" content=\"K O Arseneau&nbsp;1,&nbsp;F Cominelli, Dig Liver Dis. 2009 Aug;41(8):551-2. In summary, selective adsorption of granulocytes and monocytes from the peripheral bloodof patients with active ulcerative colitis using the extracorporal Adacolumn GMA appears tobe an extremely safe treatment modality. Although conflicting results have been reportedregarding the efficacy of Adacolumn GMA, this study by Hibi et al. 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In summary, selective adsorption of granulocytes and monocytes from the peripheral bloodof patients with active ulcerative colitis using the extracorporal Adacolumn GMA appears tobe an extremely safe treatment modality. Although conflicting results have been reportedregarding the efficacy of Adacolumn GMA, this study by Hibi et al. 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