{"id":4033,"date":"2011-04-13T13:56:00","date_gmt":"2011-04-13T13:56:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&#038;p=4033"},"modified":"2021-07-09T11:22:36","modified_gmt":"2021-07-09T11:22:36","slug":"mucosal-healing-of-esophageal-involvement-of-crohns-disease-with-granulocyte-monocyte-adsorption","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/mucosal-healing-of-esophageal-involvement-of-crohns-disease-with-granulocyte-monocyte-adsorption\/","title":{"rendered":"Mucosal healing of esophageal involvement of Crohn&#8217;s disease with granulocyte\/monocyte adsorption"},"content":{"rendered":"<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Moribata+K&amp;cauthor_id=21786316\">Kosaku Moribata<\/a><sup>&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21786316\/#affiliation-1\">1<\/a><\/sup>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Kato+J&amp;cauthor_id=21786316\">Jun Kato<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Iimura+S&amp;cauthor_id=21786316\">Sae Iimura<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Yoshida+S&amp;cauthor_id=21786316\">Satoshi Yoshida<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Shingaki+N&amp;cauthor_id=21786316\">Naoki Shingaki<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ueda+K&amp;cauthor_id=21786316\">Kazuki Ueda<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Deguchi+H&amp;cauthor_id=21786316\">Hisanobu Deguchi<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Inoue+I&amp;cauthor_id=21786316\">Izumi Inoue<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Maekita+T&amp;cauthor_id=21786316\">Takao Maekita<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Iguchi+M&amp;cauthor_id=21786316\">Mikitaka Iguchi<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Tamai+H&amp;cauthor_id=21786316\">Hideyuki Tamai<\/a>,&nbsp;<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Ichinose+M&amp;cauthor_id=21786316\">Masao Ichinose<\/a>, J Clin Apher.&nbsp;2011;26(4):225-7.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p>We report a case of a 16-year-old male who suffered from Crohn&#8217;s disease (CD) with esophageal involvement, showing remarkable improvement with granulocyte\/monocyte adsorption (GMA). The patient had been diagnosed as ileocolic CD and was treated with 5-aminosalicylate. He was admitted to our hospital with symptoms of fever, diarrhea, and odynophagia. Endoscopic examinations revealed that the exacerbation of ileocolic ulcers, and advent of ulcers in esophagus. Because of the patient&#8217;s refusal to receive corticosteroids, immunomodulators, or biologics, he underwent GMA twice a week. After 10 sessions of GMA, he entered remission with significant decrease in clinical activity. In addition, endoscopic examinations showed remarkable improvement of ileocolic ulcers and disappearance of esophageal lesions. No adverse events were observed. GMA could be effective for manifestations of CD in gastrointestinal tract other than ileum or colon.<\/p>\n<\/div>\n\n<div class=\"post-content max-w-987 mx-auto px-20 lg:px-0\">\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/21786316\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/21786316\/<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Kosaku Moribata&nbsp;1,&nbsp;Jun Kato,&nbsp;Sae Iimura,&nbsp;Satoshi Yoshida,&nbsp;Naoki Shingaki,&nbsp;Kazuki Ueda,&nbsp;Hisanobu Deguchi,&nbsp;Izumi Inoue,&nbsp;Takao Maekita,&nbsp;Mikitaka Iguchi,&nbsp;Hideyuki Tamai,&nbsp;Masao Ichinose, J Clin Apher.&nbsp;2011;26(4):225-7. We report a case of a 16-year-old male who suffered from Crohn&#8217;s disease (CD) with esophageal involvement, showing remarkable improvement with granulocyte\/monocyte adsorption (GMA). The patient had been diagnosed as ileocolic CD and was treated with 5-aminosalicylate. He was [&hellip;]<\/p>\n","protected":false},"template":"","scientific_tags":[276,147,317,275,156,311,185],"class_list":["post-4033","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-cases","scientific_tags-clinical-remission","scientific_tags-delayed-response","scientific_tags-esophage","scientific_tags-safety","scientific_tags-special-situations","scientific_tags-steroid-naive"],"acf":{"sc_authors":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mucosal healing of esophageal involvement of Crohn&#039;s disease with granulocyte\/monocyte adsorption - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/mucosal-healing-of-esophageal-involvement-of-crohns-disease-with-granulocyte-monocyte-adsorption\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mucosal healing of esophageal involvement of Crohn&#039;s disease with granulocyte\/monocyte adsorption - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Kosaku Moribata&nbsp;1,&nbsp;Jun Kato,&nbsp;Sae Iimura,&nbsp;Satoshi Yoshida,&nbsp;Naoki Shingaki,&nbsp;Kazuki Ueda,&nbsp;Hisanobu Deguchi,&nbsp;Izumi Inoue,&nbsp;Takao Maekita,&nbsp;Mikitaka Iguchi,&nbsp;Hideyuki Tamai,&nbsp;Masao Ichinose, J Clin Apher.&nbsp;2011;26(4):225-7. We report a case of a 16-year-old male who suffered from Crohn&#8217;s disease (CD) with esophageal involvement, showing remarkable improvement with granulocyte\/monocyte adsorption (GMA). The patient had been diagnosed as ileocolic CD and was treated with 5-aminosalicylate. 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We report a case of a 16-year-old male who suffered from Crohn&#8217;s disease (CD) with esophageal involvement, showing remarkable improvement with granulocyte\/monocyte adsorption (GMA). The patient had been diagnosed as ileocolic CD and was treated with 5-aminosalicylate. 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