{"id":4017,"date":"2012-04-12T13:36:00","date_gmt":"2012-04-12T13:36:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=4017"},"modified":"2021-07-09T11:26:20","modified_gmt":"2021-07-09T11:26:20","slug":"hla-drhi-and-ccr9-define-a-pro-inflammatory-monocyte-subset-in-ibd","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/hla-drhi-and-ccr9-define-a-pro-inflammatory-monocyte-subset-in-ibd\/","title":{"rendered":"HLA-DR(hi) and CCR9 Define a Pro-Inflammatory Monocyte Subset in IBD."},"content":{"rendered":"
\n

Ludvig Linton<\/a> 1<\/a><\/sup>, Mats Karlsson<\/a>, Jeanette Grundstr\u00f6m<\/a>, Eric Hjalmarsson<\/a>, Annelie Lindberg<\/a>, Emma Lindh<\/a>, Hans Glise<\/a>, Ragnar Befrits<\/a>, Izabella Janczewska<\/a>, Per Karl\u00e9n<\/a>, Ola Winqvist<\/a>, Michael Eberhardson<\/a>, Clin Transl Gastroenterol. 2012 Dec 20;3(12):e29.<\/p>\n<\/div>\n\n

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CD14(+)HLA-DR(hi) blood monocytes were increased in patients with active IBD. These monocytes exhibit a pro-inflammatory, gut-homing phenotype with regard to their TNF-\u03b1 production and expression of CCR9. Our results suggest that these monocytes are important in mediating intestinal inflammation, and provide potential therapeutic targets in IBD.<\/p>\n<\/div>\n\n

\n

https:\/\/pubmed.ncbi.nlm.nih.gov\/23254312\/<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Ludvig Linton 1, Mats Karlsson, Jeanette Grundstr\u00f6m, Eric Hjalmarsson, Annelie Lindberg, Emma Lindh, Hans Glise, Ragnar Befrits, Izabella Janczewska, Per Karl\u00e9n, Ola Winqvist, Michael Eberhardson, Clin Transl Gastroenterol. 2012 Dec 20;3(12):e29. CD14(+)HLA-DR(hi) blood monocytes were increased in patients with active IBD. These monocytes exhibit a pro-inflammatory, gut-homing phenotype with regard to their TNF-\u03b1 production and expression of CCR9. Our results suggest that these monocytes are important in […]<\/p>\n","protected":false},"template":"","scientific_tags":[247,249,159,246,312,250,248,306],"class_list":["post-4017","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-ccr9","scientific_tags-cd14","scientific_tags-crohns-disease","scientific_tags-hla-dr","scientific_tags-immunology","scientific_tags-pro-inflammatory-monocytes","scientific_tags-tnf","scientific_tags-ulcerative-colitis"],"acf":{"sc_authors":""},"yoast_head":"\nHLA-DR(hi) and CCR9 Define a Pro-Inflammatory Monocyte Subset in IBD. - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/hla-drhi-and-ccr9-define-a-pro-inflammatory-monocyte-subset-in-ibd\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HLA-DR(hi) and CCR9 Define a Pro-Inflammatory Monocyte Subset in IBD. - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Ludvig Linton 1, Mats Karlsson, Jeanette Grundstr\u00f6m, Eric Hjalmarsson, Annelie Lindberg, Emma Lindh, Hans Glise, Ragnar Befrits, Izabella Janczewska, Per Karl\u00e9n, Ola Winqvist, Michael Eberhardson, Clin Transl Gastroenterol. 2012 Dec 20;3(12):e29. 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