{"id":3962,"date":"2016-04-25T11:21:00","date_gmt":"2016-04-25T11:21:00","guid":{"rendered":"https:\/\/www.adacyte.com\/?post_type=scientific-corner&p=3962"},"modified":"2021-07-12T07:56:00","modified_gmt":"2021-07-12T07:56:00","slug":"safety-and-efficacy-of-granulocyte-monocyte-apheresis-in-steroid-dependent-active-ulcerative-colitis-with-insufficient-response-or-intolerance-to-immunosuppressants-and-or-biologics-art-trial-12-we","status":"publish","type":"scientific-corner","link":"https:\/\/www.adacyte.com\/de\/professional\/scientific-corner\/safety-and-efficacy-of-granulocyte-monocyte-apheresis-in-steroid-dependent-active-ulcerative-colitis-with-insufficient-response-or-intolerance-to-immunosuppressants-and-or-biologics-art-trial-12-we\/","title":{"rendered":"Safety and efficacy of granulocyte\/monocyte apheresis in steroid-dependent active ulcerative colitis with insufficient response or intolerance to immunosuppressants and\/or biologics (ART trial): 12-week interim results."},"content":{"rendered":"
\n

Axel Dignass<\/a> 1<\/a><\/sup>, Ayesha Akbar<\/a> 2<\/a><\/sup>, Ailsa Hart<\/a> 2<\/a><\/sup>, Sreedhar Subramanian<\/a> 3<\/a><\/sup>, Gilles Bommelaer<\/a> 4<\/a><\/sup>, Daniel C Baumgart<\/a> 5<\/a><\/sup>, Jean-Charles Grimaud<\/a> 6<\/a><\/sup>, Guillaume Cadiot<\/a> 7<\/a><\/sup>, Richard Makins<\/a> 8<\/a><\/sup>, Syed Hoque<\/a> 9<\/a><\/sup>, Guillaume Bouguen<\/a> 10<\/a><\/sup>, Bruno Bonaz<\/a> 11<\/a><\/sup> , J Crohns Colitis. 2016 Jul;10(7):812-20. <\/p>\n<\/div>\n\n

\n

At Week 12, Adacolumn provided significant clinical benefit in a large cohort of steroid-dependent ulcerative colitis patients with previous failure to immunosuppressant and\/or biologic treatment, with a favourable safety profile. These results are consistent with previous studies and support Adacolumn use in this difficult-to-treat patient subgroup.<\/p>\n<\/div>\n\n

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https:\/\/pubmed.ncbi.nlm.nih.gov\/26818659\/<\/a><\/p>\n<\/div>\n\n

\n

https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4955912\/pdf\/jjw032.pdf<\/a><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Axel Dignass 1, Ayesha Akbar 2, Ailsa Hart 2, Sreedhar Subramanian 3, Gilles Bommelaer 4, Daniel C Baumgart 5, Jean-Charles Grimaud 6, Guillaume Cadiot 7, Richard Makins 8, Syed Hoque 9, Guillaume Bouguen 10, Bruno Bonaz 11 , J Crohns Colitis. 2016 Jul;10(7):812-20.  At Week 12, Adacolumn provided significant clinical benefit in a large cohort of steroid-dependent ulcerative colitis patients with previous failure to immunosuppressant and\/or biologic treatment, with a favourable safety profile. These results are consistent with previous […]<\/p>\n","protected":false},"template":"","scientific_tags":[134,147,133,53,55],"class_list":["post-3962","scientific-corner","type-scientific-corner","status-publish","hentry","scientific_tags-biologics","scientific_tags-clinical-remission","scientific_tags-immunosuppressants","scientific_tags-refractory-patients","scientific_tags-steroid-dependent"],"acf":{"sc_authors":""},"yoast_head":"\nSafety and efficacy of granulocyte\/monocyte apheresis in steroid-dependent active ulcerative colitis with insufficient response or intolerance to immunosuppressants and\/or biologics (ART trial): 12-week interim results. - Adacyte<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.adacyte.com\/professional\/scientific-corner\/safety-and-efficacy-of-granulocyte-monocyte-apheresis-in-steroid-dependent-active-ulcerative-colitis-with-insufficient-response-or-intolerance-to-immunosuppressants-and-or-biologics-art-trial-12-we\/\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Safety and efficacy of granulocyte\/monocyte apheresis in steroid-dependent active ulcerative colitis with insufficient response or intolerance to immunosuppressants and\/or biologics (ART trial): 12-week interim results. - Adacyte\" \/>\n<meta property=\"og:description\" content=\"Axel Dignass 1, Ayesha Akbar 2, Ailsa Hart 2, Sreedhar Subramanian 3, Gilles Bommelaer 4, Daniel C Baumgart 5, Jean-Charles Grimaud 6, Guillaume Cadiot 7, Richard Makins 8, Syed Hoque 9, Guillaume Bouguen 10, Bruno Bonaz 11 , J Crohns Colitis. 2016 Jul;10(7):812-20.  At Week 12, Adacolumn provided significant clinical benefit in a large cohort of steroid-dependent ulcerative colitis patients with previous failure to immunosuppressant and\/or biologic treatment, with a favourable safety profile. 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